Nanoparticles in Biomedical Imaging

Emerging Technologies and Applications

  • Jeff W.M. Bulte
  • Michel M.J. Modo

Part of the Fundamental Biomedical Technologies book series (FBMT, volume 102)

Table of contents

  1. Front Matter
    Pages I-XVII
  2. Introduction: The Emergence of Nanoparticles as Imaging Platform in Biomedicine

    1. Front Matter
      Pages 1-1
  3. (Para)magnetic Nanoparticles: Applications in Magnetic Resonance Imaging

    1. Front Matter
      Pages 7-7
    2. Jelle O. Barentsz, Paris P. Tekkis
      Pages 25-40
    3. Akihiro Tanimoto
      Pages 41-61
    4. M.E. Kooi, S. Heeneman, M.J.A.P. Daemen, J.M.A. van Engelshoven, K.B.J.M. Cleutjens
      Pages 63-90
    5. Glenn A. Walter, Swadeshmukul Santra, Bijoy Thattaliyath, Samuel C. Grant
      Pages 91-140
    6. Patrick M. Winter, Shelton D. Caruthers, Anne H. Schmieder, Anne M. Neubauer, Gregory M. Lanza, Samuel A. Wickline
      Pages 163-182
    7. J. Manuel Perez, Charalambos Kaittanis
      Pages 183-197
    8. Eyk Schellenberger
      Pages 199-207
  4. Radiolabeled Nanoparticles: Applications in Nuclear Medicine

    1. Front Matter
      Pages 209-209
    2. Tamer Elbayoumi, Vladimir Torchilin
      Pages 211-236
    3. Peter Laverman, Gert Storm, Otto C. Boerman
      Pages 237-251
    4. Frederick L. Moffat Jr., Seza A. Gulec
      Pages 253-285
  5. Acoustically Reflective Nanoparticles: Application in Ultrasound Imaging

    1. Front Matter
      Pages 287-287
    2. Erik R. Wisner, Susannah H. Bloch
      Pages 289-310
    3. Yuko Kono, Thilo Hölscher, Robert F Mattrey
      Pages 311-325
  6. Iodinated Nanoparticles: Applications in Computed Tomography

    1. Front Matter
      Pages 369-369
    2. Andreas Sachse
      Pages 371-410
  7. Quantum Dots: Applications in Optical Imaging

    1. Front Matter
      Pages 411-411
    2. Matthew N. Rhyner, Andrew M. Smith, Xiaohu Gao, Hui Mao, Lily Yang, Shuming Nie
      Pages 413-425
    3. Dardo E. Ferrara, Charles Glaus, W. Robert Taylor
      Pages 443-461
    4. Swadeshmukul Santra, Debamitra Dutta
      Pages 463-485
    5. Willem J.M. Mulder, Gustav J. Strijkers, Rolf Koole, Celso De Mello Donega, Gert Storm, Arjan W. Griffioen et al.
      Pages 487-512
  8. Back Matter
    Pages 513-524

About this book


About the Series:

Fundamental Biomedical Technologies features titles in multidisciplinary, technology-driven areas, providing the foundations for breakthrough advances in medicine and biology. The term technology refers, in a vigorously unrestrictive sense, to a broad array of engineering disciplines, the sciences of computation and informatics, mathematical models exploiting and advancing methods of mathematical physics, and the development of novel, experimental discovery devices. Titles in this series are designed and selected to provide high-level visionary input for specialists, while presenting overviews of emerging fields for those in related areas. Volumes in this series aim to provide technologists with the material to gain competent entry into biomedical research and biomedical researchers to understand and embrace novel technological foundations and tools.

About the Series Editor:

Mauro Ferrari is a professor in the Brown Institute of Molecular Medicine, a professor of internal medicine in the division of cardiology, and the chairman of the department of biomedical engineering at the University of Texas Health Science Center in Houston, Texas. He holds concurrent professor appointments at the M.D. Anderson Cancer Center as professor of experimental therapeutics, and at Rice University in bioengineering. Dr. Ferrari is the current President of the Alliance for NanoHealth and he has spearheaded the development of the National Cancer Institute’s nanotechnology programs. Dr. Ferrari is also the founder and Editor-in-Chief of Springer’s archival journal Biomedical Microdevices.

Nanoparticles in Biomedical Imaging

Jeff W.M. Bulte and Michel M.J.J. Modo, Editors

Nanoparticles in Biomedical Imaging focuses on the use of nanoparticles as chemically engineered small entities that now have emerged as widely used diagnostic agents in biomedicine. The book is logically organized by the specific imaging modalities that are currently central in pre-clinical research and clinical routine, including magnetic resonance imaging, radionuclear imaging, ultrasound imaging, computed tomography, and optical imaging. This comprehensive title provides an expert opinion on the latest developments in biomedical imaging using nanoparticles.


Key topics:

Use of superparamagnetic iron oxide nanoparticles in magnetic resonance imaging

Radiolabeled liposomes and their applications in nuclear medicine

Ultrasound bubbles as acoustically reflective medium

Exploiting iodinated nanoparticles with computed tomography

Quantum dots: the bright future of semiconducting optical agents


Nanoparticles in Biomedical Imaging will serve as a useful and valuable resource on the fundamental science of diagnostic nanoparticles in their interactions with biological targets, providing a platform technology for clinical implementation and improved detection of disease.

About the Editors:

Jeff W.M. Bulte is currently a Professor of Radiology and a Professor of Chemical & Biomolecular Engineering at the Johns Hopkins University School of Medicine in Baltimore, USA. He serves as the Director of Cellular Imaging in the JHU Institute for Cell Engineering.

Michel M.J.J. Modo is the Wolfson Lecturer in Stem Cell Imaging at the Centre for the Cellular Basis of Behaviour and the MRC Centre for Neurodegeneration Research at the Institute of Psychiatry, King’s College London.


Tumor biomedical imaging biomedicine bone computed tomography (CT) dynamics ultrasound

Editors and affiliations

  • Jeff W.M. Bulte
    • 1
  • Michel M.J. Modo
    • 2
  1. 1.Department of RadiologyThe Johns Hopkins University School of Medicine
  2. 2.Institute of Psychiatry King’s College London, Center for the Cellular Basis of BehaviourUnited Kingdom

Bibliographic information