Retinal and Choroidal Angiogenesis

  • J.S. Penn

Table of contents

  1. Front Matter
    Pages I-XXII
  2. Angiogenesis Study Models

    1. Front Matter
      Pages 1-1
    2. M. A. Behzadian, M. Bartoli, A. B. El-Remessy, M. Al-Shabrawey, D. H. Platt, G. I. Liou et al.
      Pages 1-39
    3. Monika L. Clark, Jessica A. Fowler, John S. Penn
      Pages 41-56
    4. Susan E. Yanni, Gary W. McCollum, John S. Penn
      Pages 57-80
    5. Timothy S. Kern
      Pages 81-102
    6. Ronald P. Danis, David P. Bingaman
      Pages 103-117
  3. Molecular Characterization

    1. Front Matter
      Pages 118-118
    2. Lois E. H. Smith
      Pages 139-149
    3. Bruce A. Berkowitz
      Pages 151-168
    4. Jennifer K. Sun, George L. King
      Pages 187-202
    5. Jin Chen, Dana Brantley-Siders, John S. Penn
      Pages 203-219
    6. Arup Das, Paul G. McGuire
      Pages 259-277
    7. Jonathan M. Holmes, David A. Leske, William L. Lanier
      Pages 279-288
    8. Alexander V. Ljubimov
      Pages 289-310
    9. Juan Amaral, S. Patricia Becerra
      Pages 311-337
    10. Sergio Caballero, Nilanjana Sengupta, Lynn C. Shaw, Maria B. Grant
      Pages 339-362
  4. Applications to Clinical Conditions

    1. Front Matter
      Pages 362-362
    2. Dale L. Phelps
      Pages 363-387
    3. Gerard A. Lutty, D. Scott McLeod
      Pages 389-405
    4. Robert N. Frank
      Pages 407-418
    5. Alan L. Weiner, David A. Marsh
      Pages 419-444
    6. David P. Bingaman, Xiaolin Gu, Adrian M. Timmers, Alberta Davis
      Pages 445-526
  5. Back Matter
    Pages 545-557

About this book


Retinal and choroidal angiogenesis are the leading causes of irreversible vision loss in developed countries. For this reason, ocular angiogenesis is an intensely studied process, and the field is advancing at an astounding pace. It has become increasingly difficult to manage the vast amount of information generated by the growing group of interested investigators, thus a resource is needed that distills and summarizes our progress to date.

Retinal and Choroidal Angiogenesis provides a comprehensive, in-depth review of our current understanding of the growth of blood vessels within the eye. Renowned academic scientists, pharmaceutical scientists, and clinician-scientists have contributed chapters identifying the cellular and molecular mechanisms of retinal and choroidal angiogenesis; defining animal models of these pathologic processes; or describing the application of current tools, techniques, and theories to disease pathogenesis in humans suffering from conditions characterized by ocular angiogenesis. Additionally, novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye.

Retinal and Choroidal Angiogenesis emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance. The result is a reference work appealing to ophthalmologists interested in clinical applications, as well as to basic scientists interested in the cellular and molecular mechanisms of angiogenesis, both in the context of ocular and non-ocular conditions.


Choroidal Penn Retinal angiogenesis regulation

Editors and affiliations

  • J.S. Penn
    • 1
  1. 1.Vanderbilt University School of MedicineNashvilleU.S.A

Bibliographic information