From Cellular Signaling to Functional Plasticity

  • Jean-Marc Pequignot
  • Constancio Gonzalez
  • Colin A. Nurse
  • Nanduri R. Prabhakar
  • Yvette Dalmaz
Conference proceedings

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 536)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Honoring Pierre Dejours : His Contribution to the Study of the Role of the Arterial Chemoreceptors in the Regulation of Breathing in Humans

  3. O2 and CO2 Sensing Mechanisms in the Peripheral Arterial Chemoreceptors: Membrane Properties, Intracellular Metabolic and Genomic Events

    1. Sukhamay Lahiri, Arijit Roy, Jinquing Li, Anil Mokashi, Santhosh M. Baby
      Pages 25-32
    2. J. R. López-López, M. T. Pérez-GARCía, G. Sanz-Alfayate, Ana Obeso, Constancio Gonzalez
      Pages 33-39
    3. L. He, J. Chen, B. Dinger, K. Sanders, K. Sundar, J. Hoidal et al.
      Pages 41-46
    4. María García-Fernández, Patricia Ortega-Sáenz, Ricardo Pardal, JosÉ LÓpez-Barneo
      Pages 47-53
    5. Christopher N. Wyatt, Keith J. Buckler
      Pages 55-58
    6. Aneta Dymecka, Magdalena Marczak, Ahlam Ramadan, Piotr Suchocki, Mieczysław Pokorski
      Pages 59-64
    7. Patricia Ortega-Sáenz, María García-Fernández, Ricardo Pardal, Eleuterio Alvarez, José LÓpez-Barneo
      Pages 65-73
    8. Sergio A. Montero, Alexander Yarkov, Mónica Lemus, Herón Mendoza, Victoria Valles, Elena R. De Álvarez-Buylla et al.
      Pages 95-107
    9. Kazuo Ohtomo, Yoshiaki Hayashida, Kohko Fukuhara, Hideki Nanri, Masaharu Ikeda, Katsuaki Yoshizaki
      Pages 109-116
    10. Shinobu Osanai, Toru Takahashi, Hitoshi Nakano, Yoshinobu Ohsaki, Kenjiro Kikuchi
      Pages 117-122
    11. Christopher N. Wyatt, Keith J. Buckler
      Pages 123-127
    12. Toru Takahashi, Shinobu Osanai, Hitoshi Nakano, Yoshinobu Ohsaki, Kenjiro Kikuchi
      Pages 129-134
    13. Malin Jonsson, Sten G. E. Lindahl, Lars I. Eriksson
      Pages 135-140
  4. O2 and CO2 Sensing Mechanisms in Airway Chemoreceptors, Pulmonary Artery Smooth Muscle Cells and Other Oxygen-sensing Systems: Membrane Properties, Intracellular Metabolic and Genomic Events

    1. Giuseppe Miserocchi
      Pages 141-145
    2. Renate Paddenberg, Anna Goldenberg, Petra Faulhammer, Ruediger C Braun-Dullaeus, Wolfgang Kummer
      Pages 163-169
    3. A. Campanucci Verónica, Ian M. Fearon, Colin A. Nurse
      Pages 179-185
    4. Chris Peers, Kim N. Green, John P. Boyle
      Pages 187-192
    5. Wolfgang Kummer, Brigitte Höhler, Alexandra Sell, Jörg Hänze, Uwe Pfeil, Anna Goldenberg
      Pages 193-199
    6. Paul J Kemp, Chris Peers, Paula Miller, Anthony Lewis
      Pages 201-208
    7. Michael G. Jonz, Ian M. Fearon, Colin A. Nurse
      Pages 217-223
    8. Michael Henrich, Peter König, Marco Gruß, Tamara Fischbach, Axel Gödecke, Gunter Hempelmann et al.
      Pages 225-230
    9. Anna Bogdanova, Omolara O. Ogunshola, Christian Bauer, Mikko Nikinmaa, Max Gassmann
      Pages 231-238
    10. Kris Hughes, Mark Pickering, Deirdre M. O’leary, Aidan Bradford, Ronan G. O’regan, James F.X. Jones
      Pages 239-246
  5. Mechanisms of Communication Between Chemosensory Cells and Chemoafferent Fibers

    1. Robert S. Fitzgerald, Hay-Yan Jack Wang, Serabi Hirasawa, Machiko Shirahata
      Pages 255-261
    2. Shigeki Yamaguchi, Tomoko Higashi, Yuichi Hori, Machiko Shirahata
      Pages 263-268
    3. Machiko Shirahata, Tomoko Higashi, Jeffrey A. Mendoza, Serabi Hirasawa
      Pages 269-275
    4. Patricio Zapata, Carolina Larraín, Ricardo Fernández, Edison-Pablo Reyes
      Pages 277-283
    5. Tomoko Higashi, Shigeki Yamaguchi, J. Michael Mcintosh, Machiko Shirahata
      Pages 285-290
    6. Dong-kyu Kim, Beth A. Summers, Nanduri R. Prabhakar, Ganesh K. Kumar
      Pages 291-296
    7. Sílvia V. Conde, Emília C. Monteiro
      Pages 305-311
    8. Serabi Hirasawa, Jeffrey A. Mendoza, David B. Jacoby, Chiyoko Kobayashi, Robert S. Fitzgerald, Brian Schofield et al.
      Pages 313-319
    9. Rodrigo Varas, Julio Alcayaga, Rodrigo Iturriaga
      Pages 321-326
    10. A. J. Rico, J. Prieto-Lloret, D. F. Donnelly, C. de Felipe, Constancio Gonzalez, R. Rigual
      Pages 327-336
    11. Hideki Matsuda, Yoshiaki Hayashida, Tatsumi Kusakabe
      Pages 353-358
    12. Giuseppina Bianchi, Marisa Cacchio, L. Artese, G. Ferrero, Rapino Cinzia, A. Grilli et al.
      Pages 359-366
    13. Joana R. Batuca, Teresa C. Monteiro, EmÍlia C. Monteiro
      Pages 367-373
  6. Brainstem O2 and CO2 Sensing — Central Integration of Peripheral Chemosensory Inputs

    1. Alexander V. Gourine, K. Michael Spyer
      Pages 375-387

About these proceedings


Since 1959, the International Society of Arterial Chemoreception (ISAC) has organized in a variety of countries fifteen scientific meetings devoted to the mechanisms of peripheral arterial chemoreception and chemoreceptor reflexes. After the meeting held in Philadelphia with Sukhamay Lahiri as president, ISAC membership elected Lyon (CNRS, University Claude Bernard, France) as the site of the xv" ISAC Symposium. The Symposium was effectively held in Lyon from the 18th to the 22nd of November 2002 and Jean-Marc Pequignot was its president. The organizers were Jean-Marc Pequignot and Yvette Dalmaz Lyon (CNRS, University Claude Bernard, France) and the Scientific Committee was formed by John Carroll (University of Arkansas for Medical Sciences, USA), Constancio Gonzalez (University of Valladolid, Spain), Prem Kumar (University of Birmingham, U. K. ), Sukhamay Lahiri (University of Pennsylvania, Philadelphia, USA), Colin Nurse (McMaster University, Hamilton, Ontario, Canada), and Nanduri Prabhakar (Case Western University, Cleveland, Ohio, USA). The Symposium in Lyon intended to follow the path opened in Philadelphia gathering people working at the interface of cellular and molecular biology with researchers in the more classical topics of chemoreception pathways and reflexes. The aim was to join experts with different perspectives. Along these lines, some participants are engaged in the exploration of the intimate mechanisms of oxygen sensing and cellular responses, with their work centered in a great number of preparations covering a broad spectrum from bacteria, to chemoreceptor cells or to central nervous systems neurons.


Calcium NADPH RNA cells neurons pathophysiology physiology smooth muscle tissue transcription

Editors and affiliations

  • Jean-Marc Pequignot
    • 1
  • Constancio Gonzalez
    • 2
  • Colin A. Nurse
    • 3
  • Nanduri R. Prabhakar
    • 4
  • Yvette Dalmaz
    • 1
  1. 1.CNRS-University Claude BernardLyonFrance
  2. 2.University of ValladolidValladolidSpain
  3. 3.McMaster UniversityHamiltonCanada
  4. 4.Case Western Reserve UniversityCleveland

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2003
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-4873-3
  • Online ISBN 978-1-4419-9280-2
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site