Cancer Informatics

Essential Technologies for Clinical Trials

  • John S. Silva
  • Marion J. Ball
  • Christopher G. Chute
  • Judith V. Douglas
  • Curtis P. Langlotz
  • Joyce C. Niland
  • William L. Scherlis

Part of the Health Informatics book series (HI)

Table of contents

  1. Front Matter
    Pages i-xxvi
  2. Section 1 The Vision

    1. Front Matter
      Pages 1-1
    2. John S. Silva
      Pages 3-4
    3. Long Range Planning Committee
      Pages 17-32
    4. L. Michael Glodé
      Pages 33-43
  3. Section 2 The Infrastructure

    1. Front Matter
      Pages 45-45
    2. William L. Scherlis
      Pages 47-50
    3. Clifford Neuman
      Pages 70-78
    4. Ronald L. Larsen, Jean Scholtz
      Pages 79-96
  4. Section 3 Standards and Vocabulary

    1. Front Matter
      Pages 97-98
    2. Christopher G. Chute, Curtis P. Langlotz
      Pages 99-101
    3. Mark S. Tuttle, Keith E. Campbell, Kevin D. Keck, John S. Carter
      Pages 106-121
    4. Francis W. Hartel, Sherri de Coronado
      Pages 135-156
    5. Kent A. Spackman, M. Elizabeth Hammond
      Pages 166-175
    6. Stanley M. Huff, W. Ed Hammond, Warren G. Williams
      Pages 176-193
    7. Abdul-Malik Shakir
      Pages 194-205
    8. Robert A. Greenes, Samson Tu, Aziz A. Boxwala, Mor Peleg, Edward H. Shortliffe
      Pages 212-228
    9. Robert A. Hiatt
      Pages 229-241
  5. Section 4 Theory Into Practice

    1. Front Matter
      Pages 243-244
    2. Joyce C. Niland
      Pages 245-249
    3. Mitchell Morris
      Pages 250-269
    4. Howard S. Goldberg, Charles Safran
      Pages 280-292
    5. Joyce C. Niland, Douglas C. Stahl
      Pages 293-301
    6. Dianne M. Reeves, Douglas Hageman
      Pages 308-316
    7. Deborah K. Mayer, Susan M. Hubbard
      Pages 329-354
  6. Back Matter
    Pages 369-377

About this book


Cancer Informatics chronicles the development of the National Cancer Institute's new Cancer Informatics Infrastructure (CII) - an information management system infrastructure designed to faciliate clinical trials, provide for reliable, secure information exchange, and improve patient care. The book details the challenges involved in creating and managing such a knowledge base, including technologies, standards, and current, state-of-the-art applications.
The ultimate goal of CII is to function as an enabler of clinical trials, expediting the clinical trials lifecycle, faciliating faster and safer drug development and more appropriate treatment choices for cancer patients. Contributors address the role the CII must play in converting the growing knowledge of genes, proteins, and pathways into appropriate preventative, diagnostic, and therapeutic measures. Presented in four sections, the first provides an overview of the processes involved in moving the infrastructure for cancer from theory into practice. Sections two through four offer the latest work done in the areas of technology, cancer-specific and national standards, and applications to faciliate clinical trials.


Public Health Radiologieinformationssystem medical informatics patients primary care statistics

Editors and affiliations

  • John S. Silva
    • 1
  • Marion J. Ball
    • 2
  • Christopher G. Chute
    • 3
  • Judith V. Douglas
    • 4
    • 5
  • Curtis P. Langlotz
    • 6
  • Joyce C. Niland
    • 7
  • William L. Scherlis
    • 8
  1. 1.Center for Bioinformatics National Cancer InstituteEldersburgUSA
  2. 2.Clinical Solutions Healthlink, Inc.Johns Hopkins University School of NursingBaltimoreUSA
  3. 3.Section of Medical Information ResourcesMayo ClinicRochesterUSA
  4. 4.Johns Hopkins University School of NursingReisterstownUSA
  5. 5.Faculty of MedicineFirst Consulting GroupBaltimoreUSA
  6. 6.University of PennsylvaniaMoorestownUSA
  7. 7.Division of Information SciencesDepartment of Biostatistics City of Hope National Medical CenterDuarteUSA
  8. 8.Principal Research Scientist School of Computer ScienceCarnegie Mellon UniversityPittsburghUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag New York, Inc. 2002
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-6547-4
  • Online ISBN 978-1-4613-0063-2
  • Series Print ISSN 1431-1917
  • Buy this book on publisher's site