Myelination and Demyelination

Implications for Multiple Sclerosis

  • Seung U. Kim

Table of contents

  1. Front Matter
    Pages i-viii
  2. Neurobiology of Glial Cells

    1. Kenji Mokuno, Pierluigi Baron, Judy Grinspan, Gen Sobue, Barbara Kreider, David Pleasure
      Pages 17-28
    2. Voon Wee Yong, Myong W. Kim, Seung U. Kim
      Pages 29-48
  3. Molecular Biology of Oligodendrocytes

    1. Monique Arquint, Michael B. Tropak, Paul W. Johnson, Robert J. Dunn, John C. Roder
      Pages 61-84
  4. Electrophysiology of Glial Cells

    1. C. Krieger, S. U. Kim
      Pages 97-111
  5. Virus Infection and Demyelination

    1. Robert S. Fujinami
      Pages 121-128
    2. Richard A. Shubin, Leslie P. Weiner
      Pages 129-143
    3. B. Weinshenker, G. P. A. Rice
      Pages 145-152
  6. Neuroimmunology of multiple Sclerosis

    1. P. Jack Antel, Rolf Loertscher
      Pages 187-204
    2. D. Johnson, R. Toms, H. Weiner
      Pages 219-236
  7. Clinical Aspects of multiple Sclerosis

  8. Back Matter
    Pages 273-275

About this book


In June 1987, neurobiologists, immunologists, molecular biologists, virologists and neurologists from several countries met in Vancouver to discuss recent advances of relevance to multiple sclerosis. The symposium was a part of the 22nd Canadian Congress of Neurological Sciences meeting and was sponsored by funds from the Multiple Sclerosis Society of Canada and the Medical Research Council of Canada. The presentations covered five major topics: basic neurobiology, molecular biology, the role of viruses in demyelination, immune function and dysfunction in multiple sclerosis, and clinical magnetic resonance imaging studies. It was heartening to note that scientists from several different disciplines were working towards a common end-point: the understanding and treatment of multiple sclerosis. In this book, speakers at the symposium have each presented a chapter of their findings and discussions. In addition, some non-participants at the symposium have been invited to submit chapters in order to give this volume a more complete scope. It is hoped that the reader will find this book a useful reference for several subjects of interest to multiple sclerosis. In closing, I would like to thank the following for their help and support: the Multiple Sclerosis Society of Canada and the Medical Research Council of Canada for their financial support; the contributors of this book for their manuscripts; Dr. A. Eisen, Mrs. K. Eisen, Mrs. P. Bodnarchuk and Mrs. M. Kim for their efforts in planning and organizing the symposium; and Ms. Catherine Schikowski for her secretarial assistance. Seung U. Kim, M.D. Ph.D.


biology magnetic resonance imaging (MRI) multiple sclerosis nervous system neurobiology physiology

Editors and affiliations

  • Seung U. Kim
    • 1
  1. 1.University HospitalUniversity of British ColumbiaVancouverCanada

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1989
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-8077-4
  • Online ISBN 978-1-4613-0777-8
  • Buy this book on publisher's site