• William S. Spielman
  • Narayanan Parameswaran

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 744)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Narayanan Parameswaran, William S. Spielman
    Pages 1-11
  3. James Barwell, Denise Wootten, John Simms, Debbie L. Hay, David R. Poyner
    Pages 13-24
  4. Jennifer M. Bomberger, Narayanan Parameswaran, William S. Spielman
    Pages 25-37
  5. Tristan Bouschet, Stéphane Martin, Jeremy M. Henley
    Pages 39-48
  6. Mahita Kadmiel, Kimberly L. Fritz-Six, Kathleen M. Caron
    Pages 49-60
  7. Patrick M. Sexton, David R. Poyner, John Simms, Arthur Christopoulos, Debbie L. Hay
    Pages 61-74
  8. Joel Mainland, Hiroaki Matsunami
    Pages 75-86
  9. Asha Jacob, Rongqian Wu, Ping Wang
    Pages 87-103
  10. Narayanan Parameswaran, William S. Spielman
    Pages 105-112
  11. Back Matter
    Pages 113-114

About this book


 Among the many GPCRs discovered, the calcitonin family of receptors comprise of members that regulate a number of physiological processes and are involved in many pathological conditions. Therefore, understanding how these receptors function is a critical question in the field. When Foord and his colleagues discovered that a single transmembrane protein called Receptor Activity Modifying Proteins (RAMPs) could modulate the surface expression of GPCRs of the calcitonin family, it widely opened the field of receptor life cycle. Hundreds of studies have confirmed the importance of RAMPs in the life cycle of this receptor family. Receptor biology is a rapidly expanding field and with the advances in cell and molecular biology and in vivo techniques, it is very likely that the field of RAMPs will explode further and many unanswered questions will be answered with in the next few years.


GPCRs Narayanan Parameswaran Protein RAMPs Receptor William S. Spielman

Editors and affiliations

  • William S. Spielman
    • 1
  • Narayanan Parameswaran
    • 1
  1. 1.Department of PhysiologyMichigan State UniversityEast LansingUSA

Bibliographic information