Antimutagenesis and Anticarcinogenesis Mechanisms III

  • Giorgio Bronzetti
  • Hikoya Hayatsu
  • Silvio De Flora
  • Michael D. Waters
  • Delbert M. Shankel
  • Claire Wilson & Associates

Part of the Basic Life Sciences book series (BLSC, volume 61)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Mechanistic Approaches to Antimutagenesis and Anticarcinogenesis

    1. Silvio De Flora, Alberto Izzotti, Carlo Bennicelli
      Pages 1-16
    2. Luigi M. De Luca
      Pages 17-25
  3. Inhibition of Mutagenesis and Carcinogenesis by Extracellular Mechanisms

    1. H. Bartsch, B. Pignatelli, S. Calmels, H. Ohshima
      Pages 27-44
    2. John H. Weisburger, Bandaru S. Reddy, David P. Rose, Leonard A. Cohen, Marcia E. Kendall, Ernst L. Wynder
      Pages 45-63
    3. D. M. Shankel, S. Kuo, C. Haines, L. A. Mitscher
      Pages 65-74
    4. Kiyomi Kikugawa, Tetsuta Kato
      Pages 75-85
    5. Junko Ebata, Kazuaki Kawai, Hideyuki Furukawa
      Pages 99-102
    6. C. Ioannides, A. D. Ayrton, D. F. V. Lewis, R. Walker
      Pages 103-110
    7. Hideki Mori, Yukio Morishita, Tukuro Shinoda, Takuji Tanaka
      Pages 111-118
    8. C. Della Croce, E. Morichetti, G. Bronzetti, C. Salvadori, E. Macri
      Pages 119-125
  4. Modulation of Metabolism and Blocking of Reactive Species

    1. Thomas W. Kensler, Nancy E. Davidson, John D. Groopman, Bill D. Roebuck, Hans J. Prochaska, Paul Talalay
      Pages 127-136
    2. Bengt Jernström, Ralf Morgenstern, Peter Moldéus
      Pages 137-147
    3. R. Barale, R. Micheletti, C. Sbrana, I. Glussich, C. Scapoli, I. Barrai
      Pages 149-160
    4. David J. Meyer, Brian Coles, Jonathan Harris, Kim S. Gilmore, Kevin Raney, Thomas M. Harris et al.
      Pages 171-179
    5. Masao Hirose, Tomoyuki Shirai, Satoru Takahashi, Kumiko Ogawa, Nobuyuki Ito
      Pages 181-188
    6. R. M. Pascale, M. M. Simile, M. A. Seddaiu, L. Daino, M. A. Vinci, G. Pinna et al.
      Pages 219-237
  5. Modulation of DNA Repair and Control of Gene Expression

    1. J. A. DiPaolo, C. D. Woodworth
      Pages 239-246
    2. Takehiko Nohmi, Atsushi Hakura, Yasuharu Nakai, Masahiko Watanabe, Masami Yamada, Somay Y. Murayama et al.
      Pages 247-255
    3. H. Kasai, M.-H. Chung, F. Yamamoto, E. Ohtsuka, J. Laval, A. P. Grollman et al.
      Pages 257-262
    4. Branka Vuković-Gačić, Draga Simić
      Pages 269-277
  6. Mechanisms of Inhibition of Tumor Promotion, Progression, Invasion, and Metastases

    1. Barbour S. Warren, Thomas J. Slaga
      Pages 279-289
    2. Charles W. Boone, Gary J. Kelloff, Vernon E. Steele
      Pages 291-300
    3. M. Suganuma, S. Yoshizawa, J. Yatsunami, S. Nishiwaki, H. Furuya, S. Okabe et al.
      Pages 317-323
    4. P. Hrelia, M. Morotti, F. Vigagni, F. Maffei, M. Paolini, G. Cantelli Forti
      Pages 325-334
    5. Philip E. Hartman, Zlata Hartman
      Pages 351-366
    6. Carmia Borek, Alfred H. Merrill Jr.
      Pages 367-371
  7. Prospects in Chemoprevention of Mutation and Cancer

    1. Gary J. Kelloff, Charles W. Boone, Winfred Malone, Vernon Steele
      Pages 373-386
    2. Hikoya Hayatsu, Tomoe Negishi, Sakae Arimoto
      Pages 387-418
    3. Piero Dolara, Giovanna Caderni, Franca Bianchini, Cristina Luceri, Maria Teresa Spagnesi, Giulio Testolin
      Pages 437-445
    4. Siegfried Knasmüller, Wolfgang Huber, Rolf Schulte-Hermann
      Pages 447-457
    5. R. J. Šrám, B. Binková, J. Topinka, F. Kotěšovec, I. Fojtíková, I. Hanel et al.
      Pages 459-477
    6. R. C. von Borstel, Ursula G. G. Hennig
      Pages 479-488
  8. Back Matter
    Pages 489-494

About this book


Lifestyle, in any part of the world, is associated with the occurrence of major chronic diseases, including coronary heart disease, hypertension, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,60,70,71). The underlying evidence is, in part, based on the evidence of specific diseases in relation to dietary habits in a given geographic region, as well as changes in such disease occurrences in migrant populations from a low risk to a high risk area, and vice versa (25,42). Populations that customarily consume fruits and vegetables and also whole grain cereal products generally have a lower risk of cardiovascular diseases and specific types of cancer than populations with a lower intake of such foods, everything else being equal (63). In the last few years, research has provided mechanistic explanations as to the reasons for the protective effects of specific foods. This paper will emphasize the mechanisms whereby cancer risks are reduced by dietary modification.


DNA RNA cancer carcinogenesis gene expression genes metabolism metastasis molecular control mutagen mutagenesis prevention research tumor tumor progression

Editors and affiliations

  • Giorgio Bronzetti
    • 1
  • Hikoya Hayatsu
    • 2
  • Silvio De Flora
    • 3
  • Michael D. Waters
    • 4
  • Delbert M. Shankel
    • 5
  • Claire Wilson & Associates
    • 6
  1. 1.Istituto di Mutagenesi e Differenziamento del CNRPisaItaly
  2. 2.Okayama UniversityOkayamaJapan
  3. 3.Istituto di Igiene e Medicina PreventiaGenovaItaly
  4. 4.U.S. Environmental Protection AgencyUSA
  5. 5.University of KansasLawrenceUSA
  6. 6.USA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 1993
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6299-9
  • Online ISBN 978-1-4615-2984-2
  • Buy this book on publisher's site