Host Defenses to Intracellular Pathogens

  • Toby K. Eisenstein
  • Paul Actor
  • Herman Friedman
Conference proceedings

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 162)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Introduction and Historical Perspective

    1. Toby K. Eisenstein
      Pages 1-4
  3. Microbicidal Mechanisms of Leukocytes in Host Defenses

  4. The Immune System and Phagocytic Cell Function

    1. Stanley Cohen, Tohru Baba, Matsunobu Suko, Helen D’Silva, Takeshi Yoshida
      Pages 61-68
    2. R. S. Rappaport, G. R. Dodge
      Pages 77-82
    3. Quentin N. Myrvik, Eva S. Leake, Klara Tenner-Racz
      Pages 83-98
    4. Howard M. Johnson
      Pages 105-119
    5. Robert N. Moore, Patricia S. Steeg, Stephan E. Mergenhagen
      Pages 121-126
    6. Edmond A. Goidl, Urban Ramstedt, Thomas C. Jones
      Pages 145-150
    7. Phillip A. Scott, Jay P. Farrell
      Pages 151-155
  5. Host Defenses to Intracellular Bacteria

    1. Philippe Gros, Emil Skamene, Adrien Forget, Ben Taylor
      Pages 183-188
    2. U. G. Mason III, L. E. Greenberg, S. S. Yen, C. H. Kirkpatrick
      Pages 197-201
    3. Susan R. Watson, Ward E. Bullock
      Pages 203-215
    4. Emil Skamene, Patricia A. L. Kongshavn
      Pages 217-225
    5. Mary M. Stevenson, Patricia A. L. Kongshavn, Emil Skamene
      Pages 235-244
    6. Toby K. Eisenstein, Barnet M. Sultzer
      Pages 261-296
    7. Eleanor S. Metcalf, Alison D. O’Brien, Moira A. Laveck, William E. Biddison
      Pages 313-317
    8. Faina Varshavsky Rose, Michael F. Barile, John J. Cebra
      Pages 319-326
  6. Immunity to Rickettsia, Parasites and Fungi

  7. Mechanisms of Antiviral Immunity

    1. Peter C. Doherty, Neil Greenspan, A. Dwight Lopes, Walter Gerhard
      Pages 441-447
    2. Neal Nathanson, John R. Klein
      Pages 449-461
    3. Herman Friedman, Steven Specter, Mauro Bendinelli
      Pages 463-474
    4. Margo A. Brinton
      Pages 475-487
    5. Bracha Rager-Zisman, Celia F. Brosnan, Barry R. Bloom
      Pages 489-495
    6. Steven Specter, Mauro Bendinelli, William I. Cox, Herman Friedman
      Pages 497-501
    7. R. H. Kerman, R. Conklin, D. Cahall, C. T. Van Buren, B. D. Kahan
      Pages 517-519
  8. Back Matter
    Pages 521-538

About these proceedings


The subject matter of this volume was the basis for a confer­ ence held in Philadelphia in June, 1981, and is an important one in the contemporary area of how the host interacts with micro­ organisms. In conception, it grew out of a graduate course entitled, "The Infectious Process," which has been taught in the Department of Microbiology and Immunology at Temple University School of Medicine during the past twelve years. This course has explored the broad areas of mechanisms of microbial pathogenesis and host resistance by in-depth consideration of selected models of experimental infection and immunity, as well as the clinical literature. It is noteworthy that there is no adequate text for this material, as the subject matter naturally crosses a wide spectrum of traditional disciplinary lines, encompassing topics as diverse as the mechanisms of action of bacterial toxins, the role of complement and antibody in phagocytosis, and the importance of cross-reacting bacterial polysaccharide antigens in vaccine development. A major portion of the course has always considered "cellular immunity" as it applies to host defenses to intracellular pathogens. It is in this area that the necessity for amalgamation of information from different disciplines is most evident, for one must be intimately concerned with the interactions between the microbe and the phagocyte, both before and after specific immune recognition.


BCG Cell Mediated Lysis Cellular Processing Interferon Lymphocytes Expressing Bacterial Antigens Mechanisms Distinct Salmonella typhimurium Vivo cell surface determinants cellular immunity defense mechanism escherichia coli mediator interactions ocular disease polymorphonuclear leukocytes

Editors and affiliations

  • Toby K. Eisenstein
    • 1
  • Paul Actor
    • 2
  • Herman Friedman
    • 3
  1. 1.Temple University School of MedicinePhiladelphiaUSA
  2. 2.Smith, Kline, and French LaboratoriesPhiladelphiaUSA
  3. 3.College of MedicineUniversity of South FloridaTampaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1983
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-4483-4
  • Online ISBN 978-1-4684-4481-0
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site