Asymptomatic Atherosclerosis

Pathophysiology, Detection and Treatment

  • Morteza Naghavi

Part of the Contemporary Cardiology book series (CONCARD)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Methods for the Detection of Subclinical Atherosclerotic Cardiovascular Disease

    1. Front Matter
      Pages 87-87
    2. Morteza Naghavi, Erling Falk
      Pages 13-38
    3. Troels Thim, Mette Kallestrup Hagensen, Jacob Fog Bentzon, Erling Falk
      Pages 39-51
    4. Giovanni Cimmino, Borja Ibanez, Juan Jose Badimon
      Pages 53-66
    5. Morteza Naghavi, Erling Falk, Khurram Nasir, Harvey S. Hecht, Matthew J. Budoff, Zahi A. Fayad et al.
      Pages 77-85
  3. Methods for the Detection of Subclinical Atherosclerotic Cardiovascular Disease

  4. Non Invasive, Non Imaging, Assessment of Atherosclerotic Cardiovascular Disease

    1. Front Matter
      Pages 195-195
    2. Matthew A. Allison, Mary M. McDermott
      Pages 211-223
    3. Daniel A. Duprez, Jay N. Cohn
      Pages 225-235
    4. Craig J. Hartley, Hirofumi Tanaka
      Pages 265-275
  5. Non Invasive Structural Imaging of Subclinical Atherosclerosis

    1. Front Matter
      Pages 277-277
    2. Harvey S. Hecht
      Pages 279-284
    3. Harvey S. Hecht
      Pages 323-333
    4. Zahi A. Fayad
      Pages 357-361
    5. Chun Yuan, Hideki Ota, Xihai Zhao, Tom Hatsukami
      Pages 363-373
    6. Damini Dey, Ioannis A. Kakadiaris, Matthew J. Budoff, Morteza Naghavi, Daniel S. Berman
      Pages 375-391
  6. Non Invasive Functional Imaging of Subclinical Atherosclerosis

    1. Front Matter
      Pages 393-393
    2. A. Rauoof Malik, Iftikhar J. Kullo
      Pages 395-410
    3. Alan Rozanski, Heidi Gransar, Nathan D. Wong, Leslee J. Shaw, Michael J. Zellweger, Daniel S. Berman
      Pages 411-427
    4. Ricardo C. Cury, Anand Soni, Ron Blankstein
      Pages 433-451
  7. Invasive Assessment of ACVD

    1. Front Matter
      Pages 453-453
    2. James A. Goldstein, James E. Muller
      Pages 461-473
    3. Robert S. Schwartz, Arturo G. Touchard
      Pages 475-481
    4. Paul Schoenhagen, Anuja Nair, Stephen Nicholls, Geoffrey Vince
      Pages 483-493
    5. Charles L. Feldman, Yiannis S. Chatzizisis, Ahmet U. Coskun, Konstantinos C. Koskinas, Morteza Naghavi, Peter H. Stone
      Pages 495-506
    6. Ioannis A. Kakadiaris, Sean O’Malley, Manolis Vavuranakis, Ralph Metcalfe, Craig J. Hartley, Erling Falk et al.
      Pages 507-515
  8. Screening for Risk Assessment of Asymptomatic At-Risk Population and Identification of the Vulnerable Patient – The SHAPE Paradigm

    1. Front Matter
      Pages 516-516
    2. Morteza Naghavi, Erling Falk, Harvey S. Hecht, Michael J. Jamieson, Sanjay Kaul, Daniel S. Berman et al.
      Pages 517-535
    3. Leslee J. Shaw, Ron Blankenstein
      Pages 537-547
    4. Daming Zhu, Allen J. Taylor, Todd C. Villines
      Pages 549-567

About this book


Despite recent advances in the diagnosis and treatment of symptomatic atherosclerosis, available traditional screening methods for early detection and treatment of asymptomatic coronary artery disease are grossly insufficient and fail to identify the majority of victims prior to the onset of a life-threatening event. In Asymptomatic Atherosclerosis: Pathophysiology, Detection and Treatment, Dr. Morteza Naghavi and leading authorities from the Society for Heart Attack Prevention and Eradication (SHAPE) present a new paradigm for the screening and primary prevention of asymptomatic atherosclerosis.

The text focuses on accurate, yet underutilized, measures of subclinical atherosclerosis, notably coronary artery calcium scanning and carotid intima-media thickness measurement. The authors introduce a comprehensive approach to identifying the vulnerable patients (asymptomatic individuals at risk of a near future adverse event). Additional chapters discuss future directions towards containing the epidemic of atherosclerotic cardiovascular disease using innovative solutions such as preemptive interventional therapies (bioabsorbable stents) for stabilization of vulnerable atherosclerotic plaques, mass unconditional Polypill therapy for population-based risk reduction, and ultimately vaccination strategies to prevent the development of atherosclerosis.

Up-to-date and authoritative, Asymptomatic Atherosclerosis: Pathophysiology, Detection, and Treatment is a must-have for any cardiologist or primary care physician who wishes to practice modern preventive cardiology and manage the increasing number of asymptomatic atherosclerotic patients.

• Outlines more accurate measures of risk (coronary artery calcium and carotid intima-media thickness) than traditional risk factors (total cholesterol, LDL cholesterol, HDL cholesterol)

• Presents new multipronged strategies to aid in the early detection and treatment of high risk asymptomatic patients

Editors and affiliations

  • Morteza Naghavi
    • 1
  1. 1.Endothelix, Inc.HoustonUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2011
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-1-60327-178-3
  • Online ISBN 978-1-60327-179-0
  • Buy this book on publisher's site