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Molecular Genetics of Axial Patterning, Growth and Disease in Drosophila Eye

  • Amit Singh
  • Madhuri Kango-Singh
Book

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Abhishek K. Mishra, Simon G. Sprecher
    Pages 1-52
  3. Neha Gogia, Oorvashi Roy Puli, Akanksha Raj, Amit Singh
    Pages 53-95
  4. Brandon P. Weasner, Bonnie M. Weasner, Justin P. Kumar
    Pages 121-141
  5. Sang-Chul Nam
    Pages 143-168
  6. Shilpi Verghese, Indrayani Waghmare, Shree Ram Singh, Madhuri Kango-Singh
    Pages 215-257
  7. Karishma Gangwani, Kirti Snigdha, Mardelle Atkins, Shree Ram Singh, Madhuri Kango-Singh
    Pages 259-291
  8. Markus Friedrich, Ying Dong, Zhenyi Liu, Iris Yang
    Pages 311-342
  9. Arushi Rai, Sonia Narwal, Harsh Kanodia, Meghana Tare
    Pages 343-357
  10. Back Matter
    Pages 359-368

About this book

Introduction

Drosophila melanogaster (fruit fly) is a highly versatile model with a genetic legacy of more than a century. It provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases. One of the most important questions in biology is how a multi-cellular organism develops from a single-celled embryo. The discovery of the genes responsible for pattern formation has helped refine this question and has led to other questions, such as the role of various genetic and cell biological pathways in regulating the process of pattern formation and growth during organogenesis. The Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa.

This updated second edition covers current progress in the study of molecular genetic mechanisms of pattern formation, mutations in axial patterning, genetic regulation of growth, and more using the Drosophila eye as a model.

Keywords

developmental biology drosophila molecular genetics pattern formation neuronal eye development

Editors and affiliations

  • Amit Singh
    • 1
  • Madhuri Kango-Singh
    • 2
  1. 1.Department of BiologyUniversity of DaytonDaytonUSA
  2. 2.Department of Biology Office: SC303CUniversity of DaytonDaytonUSA

Bibliographic information