Childhood Leukemia

A Practical Handbook

  • Gregory H. Reaman
  • Franklin O. Smith

Part of the Pediatric Oncology book series (PEDIATRICO)

Table of contents

  1. Front Matter
    Pages i-x
  2. Genetics and the Epidemiology of Leukemia in Children

    1. Front Matter
      Pages 1-1
    2. Julie A. Ross, Kimberly J. Johnson, Logan G. Spector, John H. Kersey
      Pages 3-26
  3. Biology of Pediatric Leukemia

    1. Front Matter
      Pages 27-27
    2. William L. Carroll, Mignon Loh, Andrea Biondi, Cheryl Willman
      Pages 29-61
    3. Robert J. Arceci, Soheil Meshinchi
      Pages 63-76
  4. Treatment Considerations in Childhood Leukemia

    1. Front Matter
      Pages 77-77
    2. Stephen P. Hunger, Valentino Conter, Elizabeth A. Raetz, Maria Grazia Valsecchi, Guenter Henze
      Pages 79-120
    3. Brenda Gibson, John Perentesis, Todd A. Alonzo, Gertjan J. L. Kaspers
      Pages 121-160
  5. The Impact of Pharmacogenetics and Pharmacogenomics on Childhood Leukemia

    1. Front Matter
      Pages 161-161
    2. Jun J. Yang, Parinda A. Mehta, Mary V. Relling, Stella M. Davies
      Pages 163-189
  6. The Potential Role of Biologically Targeted Therapy for Childhood Leukemia

    1. Front Matter
      Pages 191-191
    2. Patrick Brown, Gregory H. Reaman, Nita L. Seibel, Pamela Kearns
      Pages 193-214
    3. Malcolm Smith, Meenakshi Devidas, Keith Wheatley, Richard B. Lock, Sally Hunsberger
      Pages 215-241
  7. Late Effects of Leukemia and Its Therapy

  8. Psychosocial Implications of Acute Leukemia Diagnosis and Treatment for Children and Families

    1. Front Matter
      Pages 283-283
    2. Anne L. Angiolillo, Momcilo Jankovic, Riccardo Haupt, Kathleen Ruccione, E. Anne Lown, Robert B. Noll
      Pages 285-301
  9. Global Strategies to Improve Leukemia Care and Outcome for Children

    1. Front Matter
      Pages 303-303
    2. Yaddanapudi Ravindranath, Hans Peter Wagner, Giuseppe Masera, Fulgencio Baez, Anjo J. P. Veerman, Jacqueline Cloos et al.
      Pages 305-322
  10. Perspectives and Future Direction

    1. Front Matter
      Pages 323-323
  11. Back Matter
    Pages 331-336

About this book


This book is a comprehensive and up-to-date compendium on all aspects of childhood acute lymphoblastic and acute myeloid leukemia, which together constitute the most frequent cancer in the pediatric age group. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike.


Acute Leukemia Biology Treatment Children

Editors and affiliations

  • Gregory H. Reaman
    • 1
  • Franklin O. Smith
    • 2
  1. 1.School of Medicine & Health SciencesGeorge Washington UniversityBethesdaUSA
  2. 2.Cincinnati Children's Hospital, Medical Center (CCHMC)University of CincinnatiCincinnatiUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-642-13780-8
  • Online ISBN 978-3-642-13781-5
  • Series Print ISSN 1613-5318
  • Buy this book on publisher's site