Gene Therapy

  • Editors
  • R. E. Sobol
  • K. J. Scanlon
  • E. Nestaas
Conference proceedings

Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 27)

Table of contents

  1. Front Matter
    Pages I-XII
  2. M. M. Gottesman
    Pages 1-16
  3. B. E. Weissman
    Pages 51-76
  4. B. Anderegg, A. Irie, K. J. Scanlon
    Pages 97-130
  5. R. Engler
    Pages 131-151
  6. H. L. Adler, P. T. Scardino
    Pages 183-194
  7. H. Glimm, C. von Kalle, R. Henschler, R. Mertelsmann
    Pages 195-210
  8. R. E. Sobol, D. Shawler, C. Van Beveren, M. Garrett, H. Fakhrai, R. Bartholomew et al.
    Pages 211-224
  9. Back Matter
    Pages 237-242

About these proceedings


This book is a collection of preclinical and clinical reports on the application of gene therapy to human disease. The two methods available for delivering therapeutic genes to diseased cells, viral and non-viral vector systems, are detailed and characterized. Several reports describe both approaches currently used in gene therapy: the introduction of a wild-type gene to restore normal gene function in diseased cells, and the use of antisense molecules to hinder abnormal gene expression. Clinical studies detail several different strategies for the treatment of cancer and cardiovascular diseases, using genetic material as therapeutic agents. The regulatory issues governing the use of gene therapy in Europe and the United States are also presented. This book highlights the range of applications and demonstrates the rapid progress being made in the field of gene therapy.


Expression Gentherapie Nucleotide gene expression gene therapy gene transfer

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1998
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-03579-5
  • Online ISBN 978-3-662-03577-1
  • Series Print ISSN 0947-6075
  • Buy this book on publisher's site