Table of contents

  1. Front Matter
    Pages i-xi
  2. Introduction into Kala-Azar

    1. Front Matter
      Pages 1-1
    2. Moazzem Hossain, Kazi M. Jamil
      Pages 3-9
  3. Therapeutic Strategy to Deal with Emergence of Drug Resistance

  4. Diagnostic Strategy Enhancing Kala-Azar Elimination Program

    1. Front Matter
      Pages 57-57
    2. Suman Rijal, Francois Chappuis, Marleen Boelaert
      Pages 59-67
    3. Eisei Noiri, Yoshifumi Hamasaki, Kousuke Negishi, Takeshi Sugaya, Kent Doi, Toshiro Fujita et al.
      Pages 69-90
  5. PKDL and Its Implications in Eliminating Kala-Azar

    1. Front Matter
      Pages 99-99
    2. Yoshitsugu Matsumoto, Chizu Sanjoba, Masahito Asada, Yasutaka Osada, Yasunobu Matsumoto
      Pages 101-110
  6. New Challenges Confronting Kala Azar Elimination Programme and Their Possible Solutions

    1. Front Matter
      Pages 125-125
    2. Moazzem Hossain, Eisei Noiri, Kazuhiko Moji
      Pages 127-137
  7. Back Matter
    Pages 147-148

About this book


Therapeutic regimens for visceral leishmaniasis (also Kala-azar, Dum-dum fever or black fever), caused by parasitic protozoa of the Leishmania genus, evolve at a pace never seen before. Spread by tiny and abundant sand flies, the parasite infects internal organs and bone marrow and if left untreated will almost always result in the death of the host. In developing countries successful diagnosis and treatment are complicated by asymptomatic cases, undernutrition and Kala-azar/HIV co-infections.

This book brings together world-renown experts writing state-of-arts review on the progress in diagnosis and treatment of visceral leishmaniasis, ultimately leading to the complete elimination of this fatal disease from South Asia. The chapters provide valuable information for disease control as well as therapy and the diagnostic improvements necessary for early treatment, subclinical detection and drug-resistant cases. The presented methods allow for points-of-care testing in the endemic area, enabling rapid detection in resource-poor settings with easy handling and low costs. 

This book provides essential information for scientists, medical practitioners and policy makers involved in the diagnosis, treatment and elimination of Kala-azar.


Biomarkers Drug-resistance LAMP PKDL Visceral Leishmaniasis

Editors and affiliations

  • T.K. Jha
    • 1
  • E. Noiri
    • 2
  1. 1.Kalazar Research CenterMuzaffarpurIndia
  2. 2., 107. Lab Nephrology & EndocrinologyThe University of TokyoBunkyo, TokyoJapan

Bibliographic information