Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules

  • Christopher G. Janson
  • Matthew J. During

Part of the Medical Intelligence Unit book series (MIUN)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Research Applications

    1. Front Matter
      Pages 1-1
    2. Peter E. Nielsen
      Pages 3-17
    3. Lionel Bastide, Bernard Lebleu, Ian Robbins
      Pages 18-29
    4. Kenneth W. Liang, Feng Liu, Leaf Huang
      Pages 30-37
    5. James E. Summerton
      Pages 89-113
    6. Jesper Wengel, Michael Petersen, Miriam Frieden, Troels Koch
      Pages 114-132
  3. Clinical Applications

    1. Front Matter
      Pages 149-149
    2. Nadia Zaffaroni, Raffaella Villa, Marco Folini
      Pages 171-180
    3. Luca Mologni, Carlo Gambacorti-Passerini
      Pages 181-194
    4. Olivier Zelphati, Jiin Felgner, Yan Wang, Xiaowu Liang, Xiaodong Wang, Philip Felgner
      Pages 195-211
    5. Henrik Ørum, Andreas Wolter, Lars Kongsbak
      Pages 212-222
    6. David R. Corey
      Pages 236-242
    7. Paul M. Smith, Günther F. Ross, Theresa M. Wardell, Robert W. Taylor, Douglass M. Turnbull, Robert N. Lightowlers
      Pages 243-251
    8. David O. Azorsa, Spyro Mousses, Natasha J. Caplen
      Pages 252-264
    9. Christopher G. Janson, Matthew J. During, Yelena Shifman, Paola Leone
      Pages 265-269
  4. Back Matter
    Pages 271-274

About this book


This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the methods available for gene targeting and modification.


DNA Expression Nucleoside Nucleotide Promoter RNA chemistry clinical application gene expression gene therapy genes information processing transcription translation

Authors and affiliations

  • Christopher G. Janson
    • 1
  • Matthew J. During
    • 2
  1. 1.Departments of Neurosurgery, Neurology and Molecular Genetics Cell and Gene Therapy CenterUMDNJ-Robert Wood Johnson Medical SchoolCamdenUSA
  2. 2.Department of Molecular Medicine and PathologyUniversity of AucklandAucklandNew Zealand

Bibliographic information