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Oligometastatic Disease

  • Vivek Verma
  • Waqar Haque
  • Gary D. Lewis
  • E. Brian Butler
  • Bin S. TehEmail author
Chapter
  • 38 Downloads
Part of the Medical Radiology book series (MEDRAD)

Abstract

Metastatic cancer patients represent a highly heterogeneous cohort with widely differing prognoses. The application of local, metastasis-directed therapies is becoming increasingly appealing, but controversies regarding patients most likely to benefit from these interventions remain. This chapter aims to evaluate the phenomenon of the oligometastatic state, rationales for utilizing local therapy (surgical and radiotherapeutic), as well as summarize the available evidence thereof. A discussion on interactions of local therapy with immunotherapy, ongoing clinical trials, and optimal patient selection is also conducted.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Vivek Verma
    • 1
  • Waqar Haque
    • 2
  • Gary D. Lewis
    • 2
    • 3
  • E. Brian Butler
    • 2
  • Bin S. Teh
    • 2
    Email author
  1. 1.Department of Radiation OncologyAllegheny General HospitalPittsburghUSA
  2. 2.Department of Radiation OncologyHouston Methodist HospitalHoustonUSA
  3. 3.Department of Radiation OncologyUniversity of Texas Medical BranchGalvestonUSA

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