An effective wound healing treatment requires proper local wound care, and targeting the systemic factors of the healing process may potentially be compromised by disease or infection in a number of ways.
The decisions regarding wound management must be based on the fundamental characteristics of each wound. A regular wound assessment is required to determine wound healing progress.
Local wound care Basic principles Infection Wound healing treatment Chronic wounds
This is a preview of subscription content, log in to check access.
Bickers DR, et al. The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. J Am Acad Dermatol. 2006;55:490–500.CrossRefGoogle Scholar
Hopman WM, et al. Associations between chronic disease, age and physical and mental health status. Chronic Dis Can. 2009;29:108–16.PubMedGoogle Scholar
Alavi A, et al. Diabetic foot ulcers: part I. Pathophysiology and prevention. J Am Acad Dermatol. 2014;70:1 e1–18; quiz 19–20.Google Scholar
Alavi A, et al. Diabetic foot ulcers: part II. Management. J Am Acad Dermatol. 2014;70:21 e21–24; quiz 45–6.Google Scholar
Ruiz ES, et al. Identifying an education gap in wound care training in United States dermatology. J Drugs Dermatol. 2015;14:716–20.PubMedGoogle Scholar
Wang PH, Huang BS, Horng HC, Yeh CC, Chen YJ. Wound healing. J Chin Med Assoc. 2018;81:94–101.CrossRefGoogle Scholar
Lindley LE, Stojadinovic O, Pastar I, Tomic-Canic M. Biology and biomarkers for wound healing. Plast Reconstr Surg. 2016;138:18S–28S.CrossRefGoogle Scholar
Brem H, et al. Primary cultured fibroblasts derived from patients with chronic wounds: a methodology to produce human cell lines and test putative growth factor therapy such as GMCSF. J Transl Med. 2008;6:75.CrossRefGoogle Scholar
Kim OY, et al. Effects of aging and menopause on serum interleukin-6 levels and peripheral blood mononuclear cell cytokine production in healthy nonobese women. Age (Dordr). 2012;34:415–25.CrossRefGoogle Scholar
Lebrun E, Kirsner RS. Frequent debridement for healing of chronic wounds. JAMA Dermatol. 2013;149:1059.CrossRefGoogle Scholar
Doerler M, Reich-Schupke S, Altmeyer P, Stucker M. Impact on wound healing and efficacy of various leg ulcer debridement techniques. J Dtsch Dermatol Ges. 2012;10:624–32.PubMedGoogle Scholar
Falanga V, et al. Maintenance debridement in the treatment of difficult-to-heal chronic wounds. Recommendations of an expert panel. Ostomy Wound Manage. 2008;Suppl:2–13; quiz 14–5.Google Scholar
Lebrun E, Tomic-Canic M, Kirsner RS. The role of surgical debridement in healing of diabetic foot ulcers. Wound Repair Regen. 2010;18:433–8.CrossRefGoogle Scholar
Cardinal M, et al. Serial surgical debridement: a retrospective study on clinical outcomes in chronic lower extremity wounds. Wound Repair Regen. 2009;17:306–11.CrossRefGoogle Scholar
Lipsky BA, Hoey C. Topical antimicrobial therapy for treating chronic wounds. Clin Infect Dis. 2009;49:1541–9.CrossRefGoogle Scholar
Lipsky BA, et al. Antimicrobial stewardship in wound care: a position paper from the British Society for Antimicrobial Chemotherapy and European Wound Management Association. J Antimicrob Chemother. 2016;71:3026–35.CrossRefGoogle Scholar