Sepsis: Control and Treatment

  • Massimo Sartelli
Part of the Hot Topics in Acute Care Surgery and Trauma book series (HTACST)


Sepsis is a complex, multifactorial syndrome which can evolve into conditions of varying severity. If left untreated, it may lead to the functional impairment of one or more vital organs or systems.

Early detection and timely therapeutic intervention can improve the prognosis and overall clinical outcome of septic patients.

Despite decades of sepsis research, no specific therapies for sepsis have emerged. Without specific therapies, management is based on control of the infection and organ support.

Early fluid resuscitation and support of vital organ function, early antibiotics, and prompt source control are the cornerstones for the treatment of patients with sepsis.


Infection Septic shock Antibiotics Source control Hemodynamic support 


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Copyright information

© World Society of Emergency Surgery and Donegal Clinical and Research Academy 2020

Authors and Affiliations

  • Massimo Sartelli
    • 1
  1. 1.Department of SurgeryMacerata HospitalMacerataItaly

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