REM Sleep Behavior Disorder (RBD)

  • Tao WangEmail author


REM sleep behavior disorder (RBD) is a parasomnia detected by vPSG showing loss of muscle atonia during REM sleep. Patients with RBD could easily recollect dream occasions associated with movements. Over the past decade, researchers brought up the theory that RBD is a prodromal stage of Parkinson’s disease (PD) and often indicates a worse prognosis among PD and RBD comorbid patients.

The diagnosis of definite RBD is specified by International Classification of Sleep Disorders-3 (ICSD-3), where PSG plays an essential role. RBD sometimes could be misdiagnosed as other sleep disorders such as NREM parasomnia, nocturnal panic attacks, nocturnal seizures, and nocturnal wandering associated with dementia, where PSG is critical in the differentiation.

Treatment of RBD is comprised of two parts, namely, injury risk reductions and medications. Although clonazepam and melatonin are commonly used, it should be noted that clonazepam has side effects on those with OSA or the elder with dementia.


RBD REM sleep vPSG Parkinson’s disease (PD) Parasomnia Diagnosis Treatment Differentiation 


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© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  1. 1.Department of Neurology, Union Hospital, Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanPeople’s Republic of China

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