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Chromatographic Reactors Based on Biological Activity

  • Ales Podgornik
  • Tatiana B. Tennikova
Chapter
Part of the Advances in Biochemical Engineering/Biotechnology book series (ABE, volume 76)

Abstract

In the last decade there were many papers published on the study of enzyme catalyzed reactions performed in so-called chromatographic reactors. The attractive feature of such systems is that during the course of the reaction the compounds are already separated, which can drive the reaction beyond the thermodynamic equilibrium as well as remove putative inhibitors. In this chapter, an overview of such chromatographic bioreactor systems is given. Besides, some immobilization techniques to improve enzyme activity are discussed together with modern chromatographic supports with improved hydrodynamic characteristics to be used in this context.

Keywords

Chromatographic reactor Chromatographic bioreactor Immobilization Chromatographic supports 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Ales Podgornik
    • 1
  • Tatiana B. Tennikova
    • 2
  1. 1.BIA Separations d. o. o.LjubljanaSlovenia
  2. 2.Institute of Macromolecular CompoundsRussian Academy of SciencesSt. PetersburgRussia

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