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Architecture of the peripheral nerve

  • P. Young
  • M. Boentert
Chapter

Keywords

Schwann Cell Myelin Basic Protein Myelin Sheath Myelinated Nerve Fiber Hereditary Neuropathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Arroyo EJ, Xu YT, Zhou L, Messing A, Peles E, Chin SY, Scherer SS (1999) Myelinating Schwann cells determine the internodal localization of Kv1.1, Kv1.2, Kvbeta2, and Caspr. J Neurocytol 28:333–347PubMedCrossRefGoogle Scholar
  2. 2.
    Balice-Gordon RJ, Bone LJ, Scherer SS (1998) Functional gap junctions in the schwann cell myelin sheath. J Cell Biol 142:1095–1104PubMedCrossRefGoogle Scholar
  3. 3.
    Bhat MA, Rios JC, Lu Y, Garcia-Fresco GP, Ching W, St Martin M, Li J, Einheber S, Chesler M, Rosenbluth J, Salzer JL, Bellen HJ (2001) Axon-glia interactions and the domain organization of myelinated axons requires neurexin IV/Caspr/Paranodin. Neuron 30:369–383PubMedCrossRefGoogle Scholar
  4. 4.
    Boiko T, Rasband MN, Levinson SR, Caldwell JH, Mandel G, Trimmer JS, Matthews G (2001) Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon. Neuron 30:91–104PubMedCrossRefGoogle Scholar
  5. 5.
    Boyle ME, Berglund EO, Murai KK, Weber L, Peles E, Ranscht B (2001) Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve. Neuron 30:385–397PubMedCrossRefGoogle Scholar
  6. 6.
    Caldwell JH, Schaller KL, Lasher RS, Peles E, Levinson SR (2000) Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses. Proc Natl Acad Sci USA 97:5616–5620PubMedCrossRefGoogle Scholar
  7. 7.
    D’Urso D, Brophy PJ, Staugaitis SM, Gillespie CS, Frey AB, Stempak JG, Colman DR (1990) Protein zero of peripheral nerve myelin: biosynthesis, membrane insertion, and evidence for homotypic interaction. Neuron 4:449–460PubMedGoogle Scholar
  8. 8.
    Einheber S, Zanazzi G, Ching W, Scherer S, Milner TA, Peles E, Salzer JL (1997) The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination. J Cell Biol 139:1495–1506PubMedCrossRefGoogle Scholar
  9. 9.
    Fannon AM, Sherman DL, Ilyina-Gragerova G, Brophy PJ, Friedrich VL, Jr, Colman DR (1995) Novel E-cadherin-mediated adhesion in peripheral nerve: Schwann cell architecture is stabilized by autotypic adherens junctions. J Cell Biol 129:189–202PubMedCrossRefGoogle Scholar
  10. 10.
    Filbin MT, Walsh FS, Trapp BD, Pizzey JA, Tennekoon GI (1990) Role of myelin P0 protein as a homophilic adhesion molecule. Nature 344:871–872PubMedCrossRefGoogle Scholar
  11. 11.
    Fjell J, Hjelmstrom P, Hormuzdiar W, Milenkovic M, Aglieco F, Tyrrell L, Dib-Hajj S, Waxman SG, Black JA (2000) Localization of the tetrodotoxin-resistant sodium channel NaN in nociceptors. Neuroreport 11:199–202PubMedGoogle Scholar
  12. 12.
    Friede RL, Samorajski T (1968) Myelin formation in the sciatic nerve of the rat. A quantitative electron microscopic, histochemical and radioautographic study. J Neuropathol Exp Neurol 27:546–570PubMedGoogle Scholar
  13. 13.
    Hess A, Young JZ (1952) The nodes of Ranvier. Proc R Soc Lond B Biol Sci 140:301–320PubMedGoogle Scholar
  14. 14.
    Ichimura T, Ellisman MH (1991) Three-dimensional fine structure of cytoskeletal-membrane interactions at nodes of Ranvier. J Neurocytol 20:667–681PubMedCrossRefGoogle Scholar
  15. 15.
    Kaplan MR, Cho MH, Ullian EM, Isom LL, Levinson SR, Barres BA (2001) Differential control of clustering of the sodium channels Na(v)1.2 and Na(v)1.6 at developing CNS nodes of Ranvier. Neuron 30:105–119PubMedCrossRefGoogle Scholar
  16. 16.
    Kordeli E, Lambert S, Bennett V (1995) AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier. J Biol Chem 270:2352–2359PubMedGoogle Scholar
  17. 17.
    Lemke G, Axel R (1985) Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin. Cell 40:501–508PubMedCrossRefGoogle Scholar
  18. 18.
    Martini R, Mohajeri MH, Kasper S, Giese KP, Schachner M (1995) Mice doubly deficient in the genes for P0 and myelin basic protein show that both proteins contribute to the formation of the major dense line in peripheral nerve myelin. J Neurosci 15:4488–4495PubMedGoogle Scholar
  19. 19.
    Menegoz M, Gaspar P, Le Bert M, Galvez T, Burgaya F, Palfrey C, Ezan P, Arnos F, Girault JA (1997) Paranodin, a glycoprotein of neuronal paranodal membranes. Neuron 19:319–331PubMedCrossRefGoogle Scholar
  20. 20.
    Michailov GV, Sereda MW, Brinkmann BG, Fischer TM, Haug B, Birchmeier C, Role L, Lai C, Schwab MH, Nave KA (2004) Axonal neuregulin-1 regulates myelin sheath thickness. Science 304:700–703PubMedCrossRefGoogle Scholar
  21. 21.
    Poliak S, Matlis S, Ullmer C, Scherer SS, Peles E (2002) Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells. J Cell Biol 159:361–372PubMedCrossRefGoogle Scholar
  22. 22.
    Previtali SC, Feltri ML, Archelos JJ, Quattrini A, Wrabetz L, Hartung H (2001) Role of integrins in the peripheral nervous system. Prog Neurobiol 64:35–49PubMedCrossRefGoogle Scholar
  23. 23.
    Rasband MN, Trimmer JS, Peles E, Levinson SR, Shrager P (1999) K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve. J Neurocytol 28:319–331PubMedCrossRefGoogle Scholar
  24. 24.
    Rasband MN, Trimmer JS, Schwarz TL, Levinson SR, Ellisman MH, Schachner M, Shrager P (1998) Potassium channel distribution, clustering, and function in remyelinating rat axons. J Neurosci 18:36–47PubMedGoogle Scholar
  25. 25.
    Rios JC, Melendez-Vasquez CV, Einheber S, Lustig M, Grumet M, Hemperly J, Peles E, Salzer JL (2000) Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination. J Neurosci 20:8354–8364PubMedGoogle Scholar
  26. 26.
    Rios JC, Melendez-Vasquez CV, Einheber S, Lustig M, Grumet M, Hemperly J, Peles E, Salzer JL (2000) Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination. J Neurosci 20:8354–8364PubMedGoogle Scholar
  27. 27.
    Samorajski T, Friede RL (1968) A quantitative electron microscopic study of myelination in the pyramidal tract of rat. J Comp Neurol 134:323–338PubMedCrossRefGoogle Scholar
  28. 28.
    Shapiro L, Doyle JP, Hensley P, Colman DR, Hendrickson WA (1996) Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin. Neuron 17:435–449PubMedCrossRefGoogle Scholar
  29. 29.
    Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA (1995) Structural basis of cell-cell adhesion by cadherins. Nature 374:327–337PubMedCrossRefGoogle Scholar
  30. 30.
    Smart SL, Lopantsev V, Zhang CL, Robbins CA, Wang H, Chiu SY, Schwartzkroin PA, Messing A, Tempel BL (1998) Deletion of the K(V)1.1 potassium channel causes epilepsy in mice. Neuron 20:809–819PubMedCrossRefGoogle Scholar
  31. 31.
    Smith KJ, Blakemore WF, Murray JA, Patterson RC (1982) Internodal myelin volume and axon surface area. A relationship determining myelin thickness? J Neurol Sci 55:231–246PubMedGoogle Scholar
  32. 32.
    Streicher R, Stoffel W (1989) The organization of the human myelin basic protein gene. Comparison with the mouse gene. Biol Chem Hoppe Seyler 370:503–510PubMedGoogle Scholar
  33. 33.
    Suter U, Scherer SS (2003) Disease mechanisms in inherited neuropathies. Nat Rev Neurosci 4:714–726PubMedCrossRefGoogle Scholar
  34. 34.
    Tait S, Gunn-Moore F, Collinson JM, Huang J, Lubetzki C, Pedraza L, Sherman DL, Colman DR, Brophy PJ (2000) An oligodendrocyte cell adhesion molecule at the site of assembly of the paranodal axo-glial junction. J Cell Biol 150:657–666PubMedCrossRefGoogle Scholar
  35. 35.
    Trapp BD (1990) Myelin-associated glycoprotein. Location and potential functions. Ann NY Acad Sci 605:29–43PubMedGoogle Scholar
  36. 36.
    Trapp BD, Hauer P, Lemke G (1988) Axonal regulation of myelin protein mRNA levels in actively myelinating Schwann cells. J Neurosci 8:3515–3521PubMedGoogle Scholar
  37. 37.
    Vabnick I, Shrager P (1998) Ion channel redistribution and function during development of the myelinated axon. J Neurobiol 37:80–96PubMedCrossRefGoogle Scholar
  38. 38.
    Wang H, Kunkel DD, Martin TM, Schwartzkroin PA, Tempel BL (1993) Heteromultimeric K+ channels in terminal and juxtaparanodal regions of neurons. Nature 365:75–79PubMedCrossRefGoogle Scholar
  39. 39.
    Young P, Boussadia O, Berger P, Leone DP, Charnay P, Kemler R, Suter U (2002) E-cadherin is required for the correct formation of autotypic adherens junctions of the outer mesaxon but not for the integrity of myelinated fibers of peripheral nerves. Mol Cell Neurosci 21:341–351PubMedCrossRefGoogle Scholar
  40. 40.
    Young P, Suter U (2003) The causes of Charcot-Marie-Tooth disease. Cell Mol Life Sci 60:2547–2560PubMedCrossRefGoogle Scholar
  41. 41.
    Zhou L, Zhang CL, Messing A, Chiu SY (1998) Temperature-sensitive neuromuscular transmission in Kv1.1 null mice: role of potassium channels under the myelin sheath in young nerves. J Neurosci 18:7200–7215PubMedGoogle Scholar

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© Steinkopff Verlag Darmstadt 2005

Authors and Affiliations

  • P. Young
  • M. Boentert

There are no affiliations available

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