Orthopedic aspects in diagnosis, clinical management and therapy of CMT patients

  • R. Forst
  • A. Ingenhorst


Spinal Muscular Atrophy Transcutaneous Electric Nerve Stimulation Tendon Transfer Flexor Digitorum Superficialis Charcot Marie Tooth 
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  1. 1.
    Aktas S, Sussman MD (2000) The radiological analysis of pes cavus deformity in Charcot Marie Tooth disease. J Pediatr Orthop Part B 9:137–140Google Scholar
  2. 2.
    Alexander IJ, Johnson KA (1989) Assessment and management of pes cavus in Charcot-Marie-tooth disease. Clin Orthop 246:273–281PubMedGoogle Scholar
  3. 3.
    Allard P, Sirois JP, Thiry PS, Geoffroy G, Duhaime M (1982) Roentgenographic study of cavus foot deformity in Friedreich ataxia patients: preliminary report. Can J Neurol Sci 9:113–117PubMedGoogle Scholar
  4. 4.
    Angus PD, Cowell HR (1986) Triple arthrodesis. A critical long-term review. J Bone Joint Surg [Br] 68:260–265Google Scholar
  5. 5.
    Bacardi BE, Alm WA (1986) Modification of the Gould operation for cavovarus reconstruction of the foot. J Foot Surg 25:181–187PubMedGoogle Scholar
  6. 6.
    Birch JG (1998) Orthopedic management of neuromuscular disorders in children. Semin Pediatr Neurol 5:78–91PubMedGoogle Scholar
  7. 7.
    Birouk N, Gouider R, Le Guern E, Gugenheim M, Tardieu S, Maisonobe T, Le Forestier N, Agid Y, Brice A, Bouche P (1997) Charcot-Marie-Tooth disease type 1A with 17p11.2 duplication. Clinical and electrophysiological phenotype study and factors influencing disease severity in 119 cases. Brain 120:813–823PubMedCrossRefGoogle Scholar
  8. 8.
    Cellerini M, Salti S, Desideri V, Marconi G (2000) MR imaging of the cauda equina in hereditary motor sensory neuropathies: correlations with sural nerve biopsy. Am J Neuroradiol 21:1793–1798PubMedGoogle Scholar
  9. 9.
    Chalekson CP, Brown RE, Gelber DA, Haws MJ (1999) Nerve decompression at the wrist in patients with Charcot-Marie-Tooth disease. Plast Reconstr Surg 104:999–1002PubMedGoogle Scholar
  10. 10.
    Charles YP, Axt M, Doderlein L (2001) Dynamic pedobarography in postoperative evaluation of pes cavovarus. Rev Chir Orthop Reparatrice Appar Mot 87:696–705PubMedGoogle Scholar
  11. 11.
    Daher YH, Lonstein JE, Winter RB, Bradford DS (1986) Spinal deformities in patients with Charcot-Marie-tooth disease. A review of 12 patients. Clin Orthop 202:219–222PubMedGoogle Scholar
  12. 12.
    Döderlein L (1999) [Soft tissue operations in neuromuscular foot deformities]. Orthopäde 28:151–158PubMedGoogle Scholar
  13. 13.
    Exner GU (1987) Pes valgoplanus in Friedreich and Charcot-Marie-Tooth-Hoffmann disease. Z Orthop Ihre Grenzgeb 125:298–301PubMedGoogle Scholar
  14. 14.
    Fenton CF 3rd, McGlamry ED, Perrone M (1982) Severe pes cavus deformity secondary to Charcot-Marie-Tooth disease: a case report. J Am Podiatry Assoc 72:171–175PubMedGoogle Scholar
  15. 15.
    Fenton CF 3rd., Schlefman BS, McGlamry ED (1984) Surgical considerations in the presence of Charcot-Marie-Tooth disease. J Am Podiatry Assoc 74:490–498PubMedGoogle Scholar
  16. 16.
    Fuller JE, DeLuca PA (1995) Acetabular dysplasia and Charcot-Marie-Tooth disease in a family. A report of four cases. J Bone Joint Surg [Am] 77:1087–1091Google Scholar
  17. 17.
    Ghanem I, Zeller R, Seringe R (1996) [The foot in hereditary motor and sensory neuropathies in children]. Rev Chir Orthop Reparatrice Appar Mot 82:152–160PubMedGoogle Scholar
  18. 18.
    Gould N (1984) Surgery in advanced Charcot-Marie-Tooth disease. Foot Ankle 4:267–273PubMedGoogle Scholar
  19. 19.
    Guyton GP, Mann RA (2000) The pathogenesis and surgical management of foot deformity in Charcot-Marie-Tooth disease. Foot Ankle Clin 5:317–326PubMedGoogle Scholar
  20. 20.
    Harding AE, Thomas PK (1980) The clinical features of hereditary motor and sensory neuropathy types I and II. Brain 103:259–280PubMedGoogle Scholar
  21. 21.
    Hassel B (1998) Improvement of muscle function in Charcot-Marie-Tooth disease by transcutaneous electric nerve stimulation. Muscle Nerve 21:267–268PubMedCrossRefGoogle Scholar
  22. 22.
    Holmes JR, Hansen ST Jr (1993) Foot and ankle manifestations of Charcot-Marie-Tooth disease. Foot Ankle 14:476–486PubMedGoogle Scholar
  23. 23.
    Imhauser G (1984) [Treatment of severe concave clubfoot in neural muscular atrophy]. Z Orthop Ihre Grenzgeb 122:827–834PubMedCrossRefGoogle Scholar
  24. 24.
    Jahss MH (1983) Evaluation of the cavus foot for orthopedic treatment. Clin Orthop 181:52–63PubMedGoogle Scholar
  25. 25.
    Kucukkaya M, Kabukcuoglu Y, Kuzgun U (2002) Management of the neuromuscular foot deformities with the Ilizarov method. Foot Ankle 23:135–141PubMedGoogle Scholar
  26. 26.
    Kumar SJ, Marks HG, Bowen JR, MacEwen GD (1985) Hip dysplasia associated with Charcot-Marie-Tooth disease in the older child and adolescent. J Pediatr Orthop 5:511–514PubMedGoogle Scholar
  27. 27.
    Kuruvilla A, Costa JL, Yoder DM, Andriacchi TP (2000) Characterization of gait parameters in patients with Charcot-Marie-Tooth disease. Neurol India 48:49–55PubMedGoogle Scholar
  28. 28.
    Lindeman E, Leffers P, Reulen J, Spaans F, Drukker J (1998) Quadriceps strength and timed motor performances in myotonic dystrophy, Charcot-Marie-Tooth disease, and healthy subjects. Clin Rehabil 12:127–135PubMedCrossRefGoogle Scholar
  29. 29.
    Lindeman E, Spaans F, Reulen J, Leffers P, Drukker J (1999) Progressive resistance training in neuromuscular patients. Effects on force and surface EMG. J Electromyogr Kinesiol 9:379–384PubMedGoogle Scholar
  30. 30.
    Mackin GA, Gordon MJ, Neville HE, Ringel SP (1999) Restoring hand function in patients with severe polyneuropathy: the role of electromyography before tendon transfer surgery. J Hand Surg [Am] 24:732–742CrossRefGoogle Scholar
  31. 31.
    Mann DC, Hsu JD (1992) Triple arthrodesis in the treatment of fixed cavovarus deformity in adolescent patients with Charcot-Marie-Tooth disease. Foot Ankle 13:1–6PubMedGoogle Scholar
  32. 32.
    Mann RA, Missirian J (1988) Pathophysiology of Charcot-Marie-Tooth disease. Clin Orthop 234:221–228PubMedGoogle Scholar
  33. 33.
    McGann R, Gurd A (2002) The association between Charcot-Marie-Tooth disease and developmental dysplasia of the hip. Orthopedics 25:337–339PubMedGoogle Scholar
  34. 34.
    Medhat MA, Krantz H (1988) Neuropathic ankle joint in Charcot-Marie-Tooth disease after triple arthrodesis of the foot. Orthop Rev 17:873–880PubMedGoogle Scholar
  35. 35.
    Metaxiotis D, Accles W, Pappas A, Doederlein L (2000) Dynamic pedobarography (DPB) in operative management of cavovarus foot deformity. Foot Ankle Int 21:935–947PubMedGoogle Scholar
  36. 36.
    Michelinakis E, Vourexakis H (1981) Tendon transfer for intrinsic-muscle paralysis of the thumb in Charcot-Marie-Tooth neuropathy. Hand 13:276–278PubMedGoogle Scholar
  37. 37.
    Miller GM, Hsu JD, Hoffer MM, Rentfro R (1982) Posterior tibial tendon transfer: a review of the literature and analysis of 74 procedures. J Pediatr Orthop 2:363–370PubMedGoogle Scholar
  38. 38.
    Miller MJ, Williams LL, Slack SL, Nappi JF (1991) The hand in Charcot-Marie-Tooth disease. J Hand Surg [Br] 16:191–196CrossRefGoogle Scholar
  39. 39.
    Mosca VS (2001) The cavus foot. J Pediatr Orthop 21:423–424PubMedCrossRefGoogle Scholar
  40. 40.
    Mulder T, den Otter R, van Engelen B (2001) The regulation of fine movements in patients with Charcot Marie Tooth, type Ia: some ideas about continuous adaptation. Motor Control 5:200–214PubMedGoogle Scholar
  41. 41.
    Mulier E, De Rijcke J, Fabry G, Mulier JC (1990) Triple arthrodesis in neuromuscular disorders. Acta Orthop Belg 56:557–561PubMedGoogle Scholar
  42. 42.
    Njegovan ME, Leonard EI, Joseph FB (1997) Rehabilitation medicine approach to Charcot-Marie-Tooth disease. Clin Podiatr Med Surg 14:99–116PubMedGoogle Scholar
  43. 43.
    Oganesian OV, Istomina IS (1991) Talipes equinocavovarus deformities corrected with the aid of a hinged-distraction apparatus. Clin Orthop 266:42–50PubMedGoogle Scholar
  44. 44.
    Oganesyan OV, Istomina IS, Kuzmin VI (1996) Treatment of equinocavovarus deformity in adults with the use of a hinged distraction++ apparatus. J Bone Joint Surg [Am] 78:546–556Google Scholar
  45. 45.
    Olney B (2000) Treatment of the cavus foot. Foot Ankle Clin 5:305–315PubMedGoogle Scholar
  46. 46.
    Osebold WR, Lester EL, Watson P (2002) Observations on the development of the acetabulum following Chiari osteotomy. The Iowa Orthopaedic Journal 22:66–74PubMedGoogle Scholar
  47. 47.
    Osebold WR, Lester EL, Watson P (1997) Dynamics of hip joint remodeling after Chiari osteotomy. 10 patients with neuromuscular disease followed for 8 years. Acta Orthop Scand 68:128–132PubMedGoogle Scholar
  48. 48.
    Pailthorpe CA, Benson MK (1992) Hip dysplasia in hereditary motor and sensory neuropathies. J Bone Joint Surg [Br] 74:538–540Google Scholar
  49. 49.
    Petrela M, Xhumari A, Buda L, Kuqo A, Baboci H (1991) [Compression of the conus and the hypertrophic form of Charcot-Marie disease]. Rev Neurol (Paris) 147:397–399Google Scholar
  50. 50.
    Quintart C, Baillon JM, Libotte M (1999) [Pathologic fracture of the tibia associated with Charcot-Marie-Tooth disease]. Acta Orthop Belg 65:105–108PubMedGoogle Scholar
  51. 51.
    Raikin SM (2002) Failure of triple arthrodesis. Foot Ankle Clin 7:121–133PubMedGoogle Scholar
  52. 52.
    Riley Jr WB, Mann RJ, Burkhalter WE (1980) Extensor pollicis longus opponensplasty. J Hand Surg [Am] 5:217–220Google Scholar
  53. 53.
    Rosen SA, Wang H, Cornblath DR, Uematsu S, Hurko O (1989) Compression syndromes due to hypertrophic nerve roots in hereditary motor sensory neuropathy type I. Neurology 39:1173–1177PubMedGoogle Scholar
  54. 54.
    Roy DR, Al-Sayyad MJ (2001) Complications of surgery of the foot and ankle in hereditary neurologic disorders. Clin Orthop 391:181–187PubMedGoogle Scholar
  55. 55.
    Sabir M, Lyttle D (1983) Pathogenesis of pes cavus in Charcot-Marie-Tooth disease. Clin Orthop 175:173–178PubMedGoogle Scholar
  56. 56.
    Sabir M, Lyttle D (1984) Pathogenesis of Charcot-Marie-Tooth disease. Gait analysis and electrophysiologic, genetic, histopathologic, and enzyme studies in a kinship. Clin Orthop 184:223–235PubMedGoogle Scholar
  57. 57.
    Saltzman CL, Fehrle MJ, Cooper RR, Spencer EC, Ponseti IV (1999) Triple arthrodesis: twenty-five and forty-four-year average follow-up of the same patients. J Bone Joint Surg [Am] 81:1391–1402Google Scholar
  58. 58.
    Samilson RL, Dillin W (1983) Cavus, cavovarus, and calcaneocavus. An update. Clin Orthop 177:125–132PubMedGoogle Scholar
  59. 59.
    Sammarco GJ, Taylor R (2001) Cavovarus foot treated with combined calcaneus and metatarsal osteotomies. Foot Ankle 22:19–30PubMedGoogle Scholar
  60. 60.
    Santavirta S, Turunen V, Ylinen P, Konttinen YT, Tallroth K (1993) Foot and ankle fusions in Charcot-Marie-Tooth disease. Arch Orthop Trauma Surg 112:175–179PubMedGoogle Scholar
  61. 61.
    Shapiro F, Bresnan MJ (1982) Orthopaedic management of childhood neuromuscular disease. Part II: peripheral neuropathies, Friedreich’s ataxia, and arthrogryposis multiplex congenita. J Bone Joint Surg [Am] 64:949–953Google Scholar
  62. 62.
    Shapiro F, Specht L (1993) The diagnosis and orthopaedic treatment of childhood spinal muscular atrophy, peripheral neuropathy, Friedreich ataxia, and arthrogryposis. J Bone Joint Surg [Am] 75:1699–1714Google Scholar
  63. 63.
    Siegel IM (1989) Neuropathic ankle in CMT disease [letter]. Orthop Rev 18:267PubMedGoogle Scholar
  64. 64.
    Siegel IM (1994) Management of kineceptive loss in CMT with an elastic ankle support. Muscle Nerve 17:827PubMedGoogle Scholar
  65. 65.
    Vinci P, Perelli SL (2002) Footdrop, foot rotation, and plantarflexor failure in Charcot-Marie-Tooth disease. Arch Phys Med Rehabil 83:513–516PubMedCrossRefGoogle Scholar
  66. 66.
    Walker JL, Nelson KR, Heavilon JA, Stevens DB, Lubicky JP, Ogden JA, VandenBrink KA (1994) Hip abnormalities in children with Charcot-Marie-Tooth disease. J Pediatr Orthop 14:54–59PubMedGoogle Scholar
  67. 67.
    Walker JL, Nelson KR, Stevens DB, Lubicky JP, Ogden JA, VandenBrink KD (1994) Spinal deformity in Charcot-Marie-Tooth disease. Spine 19:1044–1047PubMedGoogle Scholar
  68. 68.
    Wetmore RS, Drennan JC (1989) Long-term results of triple arthrodesis in Charcot-Marie-Tooth disease. J Bone Joint Surg [Am] 71:417–422Google Scholar
  69. 69.
    Windhager R, Lack W, Kutschera H, Wimberger W, Mayr M (1989) Clinical and radiologic comparison of “idiopathic” and “neurogenic” pes cavus. Z Orthop Ihre Grenzgeb 127:169–173PubMedGoogle Scholar
  70. 70.
    Wood VE, Huene D, Nguyen J (1995) Treatment of the upper limb in Charcot-Marie-Tooth disease. J Hand Surg [Br] 20:511–518CrossRefGoogle Scholar
  71. 71.
    Wukich DK, Bowen JR (1989) A long-term study of triple arthrodesis for correction of pes cavovarus in Charcot-Marie-Tooth disease. J Pediatr Orthop 9:433–437PubMedGoogle Scholar
  72. 72.
    Zwipp H, Rammelt S, Dahlen C, Reichmann H (1999) The Charcot joint. Orthopäde 28:550–558PubMedGoogle Scholar

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© Steinkopff Verlag Darmstadt 2005

Authors and Affiliations

  • R. Forst
  • A. Ingenhorst

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