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Application of microcomputers in the study of microbial processes

  • Werner A. Hampel
Conference paper
Part of the Advances in Biochemical Engineering book series (ABE, volume 13)

Abstract

The applications of computers and microcomputers in particular interfaced to bench-top bioreactors are briefly discussed. Compact, quick-access microcomputers (e.g., desk-top calculators) offer the possibility of on-line data acquisition and analysis as well as process control (sequencing, interactive control) with relatively high efficiency at reasonably low costs of installation in laboratory experiments. The configuration of such a computerized system is described in detail along with the capabilities and features of interfacing hardware components. The limits in applicability due to slow operating speeds of fully developed microcomputer systems in particular are pointed out and a survey on investment costs for high-performance, compact desk-top calculators and some peripheral devices is given. Examples of on-line acquisition of several directly accessible environmental process parameters and computations of directly inaccessible state variables are presented in the form of type-writer print-outs. The advantages of on-line experiments for establishing sophisticated control algorithms and for studying the physiological behaviour of the microbial population are demonstrated.

Keywords

Central Processing Unit Microbial Process Respiratory Quotient Random Access Memory Peripheral Device 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Symbols

ALU

arithmetic and logic unit

cL

concentration of dissolved oxygen (mMol l−1)

cL*

concentration of dissolved oxygen in equilibrium with air (mMol l−1)

cm

specific substrate uptake rate for cell maintenance (g-S g-X−1 h−1)

CPU

central processing unit

CRT

cathode ray tube

DO

dissolved oxygen

DDC

direct digital control

DSC

direct setpoint control

F

gas flow rate (mMol h−1)

Fs

substrate feed rate (g-S h−1 l−1)

h

absolute humidity (dimensionless)

KLa

volumetric oxygen transfer coefficient (h−1)

P

absolute pressure (Pa)

Q

specific metabolic rate (mMol g-X−1 h−1)

RAM

random access memory

ROM

read only memory

RQ

respiratory quotient (dimensionless)

S

substrate concentration (mMol l−1)

t

time (h)

T

temperature (°C)

V

liquid volume in reactor (1)

w

mole fraction of inert gas in air (dimensionless)

x

mole fraction of oxygen in air (dimensionless)

X

biomass concentration (g l−1)

y

mole fraction of carbon dioxide in air (dimensionless)

Y

yield coefficient (dimensionless)

Greek Letters

μ

specific growth rate (h−1)

Subcripts

a

initial conditions

i

inlet

o

outlet

s

substrate

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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Werner A. Hampel
    • 1
  1. 1.Institute of Biochemical Technology and MicrobiologyUniversity of Technology ViennaWienAustria

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