- 848 Downloads
In this chapter, we briefly outline the basic preliminary information about the heart as a pump in the blood circulatory system, its structure, and major component systems. The material presented here is a series of short excerpts from A.C. Guyton and J.E. Hall’s “Textbook of Medical Physiology” , which is meant to introduce readers without biological background to the basic terminology, definitions and functions of the heart systems as part of the whole organ. We will look at additional physiological information in greater depth in later chapters.
Here we also emphasize that heart arrhythmias and fibrillation continue to be dangerous heart diseases, the mechanisms of which have not been clearly understood until recently. Mathematical modeling and computer simulations are characterized as modern tools for scientific research in this area.
KeywordsVentricular Fibrillation Spiral Wave Blood Circulatory System Heart Contractility Simplify Block Diagram
Unable to display preview. Download preview PDF.
- 1.Guyton, A.C. and J.E. Hall, Textbook of Medical Physiology. 9th ed. 1996, Philadelphia: W.B. Saunders.Google Scholar
- 2.Hoffman, B.F. and P.F. Cranefield, Electrophysiology of the Heart. 1960, New York: McGraw-Hill.Google Scholar
- 3.Zipes, D. and J. Jalife, eds. Cardiac Electrophysiology: From Cell to Bedside. 2nd ed. 1995, W.B. Saunders: Philadelphia.Google Scholar
- 4.Weiss, J.N., Transition of Sinus Rhythm to VT to VF, Unpublished.Google Scholar
- 5.Rajskina, M.E., Ventricular Fibrillation and Sudden Coronary Death. 1999: Kluwer Academic Publishers.Google Scholar
- 6.Bers, D.M., Excitation-Contraction Coupling and Cardiac Contractile Force. 2nd ed. 2001, Norwell, MA: Kluwer Academic Publishers.Google Scholar
- 9.Keener, J. and J. Sneyd, Mathematical Physiology. 2nd ed. 2001: Springer-Verlag.Google Scholar
- 10.Bassingthwaighte, J.B., Toward modeling the human physiome. Adv Exp Med Biol, 1999. 382: 331–339.Google Scholar