Partial Left Ventriculectomy

  • Richard J. Kaplon
  • Patrick M. McCarthy
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 225)


End-stage heart failure currently affects 1 % of people under 55 years old, 9% of people over 80 years old, and is expected to continue to increase in prevalence.1 Despite improvements in pharmacologic management of heart failure with newer agents such as angiotensin-converting enzyme inhibitors or beta-blockers such as carvedilol, approximately 25% of patients die while awaiting heart transplantation. 2-4 Even with attempts at expanding the donor pool through “alternate recipient lists”, the limited number of hearts available for transplantation has plateaued.5,6 Ventricular-assist devices (VAD) have been effective as bridges to transplantation for those patients refractory to medical therapy, however, present use of VADs as destination therapy remains investigational.7-9 Clinical attempts at cardiomyoplasty and xenotransplantation have, thus far, been generally disappointing.10,11


Cardiac Index Papillary Muscle Mitral Valve Repair Mitral Leaflet Bovine Pericardium 
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© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Richard J. Kaplon
  • Patrick M. McCarthy

There are no affiliations available

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