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Control of Body Segment Differentiation in Drosophila by the Bithorax Gene Complex

  • E. B. Lewis
Chapter

Abstract

The bithorax complex (BX-C) in Drosophila is a giant cluster of closely linked genes that plays a major role in determining the segmentation pattern of the organism. From developmental and cytogenetic studies of this complex it now appears that orderly derepression of BX-C genes controls the orderly differentiation of body segments commencing with the thorax and proceeding posteriorly. The available evidence also suggests that the level of development which a given one of these segments achieves is a function of the particular subset of BX-C genes that is active in that segment. This paper summarizes the current status of our knowledge of what the BX-C genes do during development and how they are regulated.

Keywords

Genital Disc Rearran Gement Osition Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • E. B. Lewis
    • 1
  1. 1.Division of BiologyCalifornia Institute of TechnologyPasadenaUSA

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