Effect of Yeast Extract on Growth Kinetics of Monascus purpureus

  • Daniela Gerevini Pereira
  • Beatriz Vahan KilikianEmail author
Part of the ABAB Symposium book series (ABAB)


Growth kinetics and red pigment production of Monascus purpureus CCT 3802 was studied. A reproducible inoculum with extremely dispersed hyphae for bioreactor runs was obtained through a two-step cultivation in a shaker. First, the spores were cultivated in a complex medium rendering a suspension of vegetative cells. In the second step these cells were grown in a semisynthetic medium. Two types of media were employed in the bioreactor runs: a semisynthetic (glucose, salts, and yeast extract), and a synthetic, without yeast extract. The inclusion of yeast extract, caused an increase in cell yield on glucose (Y x/s )as high as 40%. Also, yeast extract probably yielded a higher proportion of ®red pigment associated with the cell, relative to the synthetic medium. On the other hand, cells grown on the synthetic medium were slightly higher producers of red soluble pigments.

Index Entries

Monascus purpureas yeast extract red pigment kinetics 


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  1. 1.
    Francis, F. J. (1989), Crit. Rev. Food Sci. Nutr. 28(4), 273–314.CrossRefGoogle Scholar
  2. 2.
    Multon, J. L. (1992), SPIVNNAdditifs et auxiliares de Fabrication dans les Industries Agro-alimentares, Tec. et Doc. Lavoisier, ed., Apriaspi.Google Scholar
  3. 3.
    Rosenblitt, A., Agosin, E., Delgado, J., and Pérez-Correa, R. (2000), Biotechnol Prog. 16, 152–162.CrossRefGoogle Scholar
  4. 4.
    Went, F. A. F. C. (1985), Ann. Sci. Nat. Bot. Ser. 8, 111–148.Google Scholar
  5. 5.
    Fabre, C. E., Santerre, A. L., Baberian, R., Pareilleux, A., Goma, G., and Blanc, P. J. (1993), J. Food Sci. 58(5), 1099–1110.CrossRefGoogle Scholar
  6. 6.
    Wong, H. C. and Bau, Y. S. (1977), Plant Physiol. 60, 578–581.CrossRefGoogle Scholar
  7. 7.
    Lin, T. F. and Demain, A. L. (1991), Appl. Microbiol. Biotechnol. 36, 70–75.CrossRefGoogle Scholar
  8. 8.
    Juzlova, P., Martinková, L., and Kren, V. (1996), J. Ind. Microbiol. 16, 163–170.CrossRefGoogle Scholar
  9. 9.
    Pastrana, L., Blanc, P. J., Santerre, A. L., Loret, M., and Goma, G. (1995), Process Biochem. 30(4), 333–341.Google Scholar
  10. 10.
    Hamdi, M., Blanc, P. J., and Goma, G. (1997), Bioprocess Eng. 17(2), 75–79.Google Scholar
  11. 11.
    Hamdi, M., Blanc, P. J., and Goma, G. (1996), Process Biochem. 31(6), 543–547.CrossRefGoogle Scholar
  12. 12.
    Pastrana, L. and Goma, G. (1995), Process Biochem. 30(7), 607–613.Google Scholar

Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Daniela Gerevini Pereira
    • 1
  • Beatriz Vahan Kilikian
    • 1
    Email author
  1. 1.Escola Politécnica de São PauloDepartamento de Engenharia QuímicaSão Paulo-SPBrazil

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