In Vitro Effects of d(+) And l(-) Ozolinone on Sodium and Potassium Fluxes in Human Erythrocytes
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Several observations suggest that diuretic drugs may decrease renal Na reabsorption by direct inhibition of Na transport carrier in different segments of the nephron [1,2]. Ouabain inhibits basolateral sodium reabsorption, which is catalyzed by the Na, K pump; loop diuretics, like furosemide and bumetanide, cause natriuresis by inhibition of the Na, K, Cl cotransport system, which is located in the luminal side of Henle’s loop cells.
KeywordsHuman Erythrocyte Tienilic Acid Passive Membrane Hypertensive Drug Diuretic Drug
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