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Plasma Levels of Human Atrial Natriuretic Peptide in Chronic Uremic Patients

  • G. Cannella
  • S. Ghielmi
  • A. Rodella
  • M. Gaggiotti
  • G. Brunori
  • M. Quinzanini
  • R. Maiorca
Chapter
  • 13 Downloads
Part of the Developments in Nephrology book series (DINE, volume 18)

Abstract

So far, 3 atrial natriuretic polypeptides (ANP) have been isolated from human cardiocytes and, among them, the α-type seems to be preferentially released into the blood stream (1). In normal man, saline infusion or high sodium intake increase plasma α-hANP levels while the opposite is true on low sodium diet (2). These observations seem to suggest that α-hANP is involved in extracellular fluid volume (ECFV) homeostasis. This study was undertaken to obtain some more insight about the involvement of α-hANP in the pathophysiology of body fluid volume in man.

Keywords

Dialyze Patient Atrial Natriuretic Peptide Uremic Patient Extracellular Fluid Volume Chronic Dialyze Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Sugarawa, A., Nakao, K., Morii, N., Sakamoto, M., Suda, M., Shimokura, M., Kiso, Y., Kihara, M., Yamory, Y., Nishimura, K., Soneda, J., Ban, T., Imura, M. Biochem. and Biophys. Res. Comm. 129: 439–446, 1985.CrossRefGoogle Scholar
  2. 2.
    Sagnella, G.A., Markandu, N.D., Share, A.C., Mc Gregor, G.A. Lancet, ii: 1208–1211, 1985.CrossRefGoogle Scholar
  3. 3.
    Sagnella, G.A., Mac Gregor, G.A. Nature, 309: 666–667, 1984.PubMedCrossRefGoogle Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1987

Authors and Affiliations

  • G. Cannella
    • 1
  • S. Ghielmi
    • 2
  • A. Rodella
    • 2
  • M. Gaggiotti
    • 1
  • G. Brunori
    • 1
  • M. Quinzanini
    • 2
  • R. Maiorca
    • 1
  1. 1.Department of Nephrology, School of MedicineSpedali Civili and University of BresciaBresciaItaly
  2. 2.Department of Clinical Chemistry, School of MedicineSpedali Civili and University of BresciaBresciaItaly

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