Plasma Levels of Human Atrial Natriuretic Peptide in Chronic Uremic Patients
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So far, 3 atrial natriuretic polypeptides (ANP) have been isolated from human cardiocytes and, among them, the α-type seems to be preferentially released into the blood stream (1). In normal man, saline infusion or high sodium intake increase plasma α-hANP levels while the opposite is true on low sodium diet (2). These observations seem to suggest that α-hANP is involved in extracellular fluid volume (ECFV) homeostasis. This study was undertaken to obtain some more insight about the involvement of α-hANP in the pathophysiology of body fluid volume in man.
KeywordsDialyze Patient Atrial Natriuretic Peptide Uremic Patient Extracellular Fluid Volume Chronic Dialyze Patient
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