Correlation between Blood Pressure and K+ Fluxes in Essential Hypertensive Patients Treated For 2 Years with Cicletanine
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[Leak (+)] = increased passive entry of Na+ in about 15 to 30% of human hypertensives (Leak (+) hypertensives).
[Co (-)] = decreased ability of the furosemide-sensitive Na+, K+ cotransport system to extrude a cell Na+-load in about 30 to 40% of human hypertensives (Co (-) hypertensives).
[Counter (+)] = increased maximal rate of Na+: Li+ countertransport in about 20 to 40% of human hypertensives (Counter (+) hypertensives).
[Pump (-)] = decreased apparent affinity of the Na+, K+ pump for internal Na+ in about 5–10% of human hypertensives.
KeywordsBlood Pressure Essential Hypertension Antihypertensive Treatment Extensive Investigation Antihypertensive Effect
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