Surgical restaging after 3 or 6 courses of MOPP chemotherapy in Hodgkin’s disease
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A majority of patients with Hodgkin’s disease can achieve complete remission and recovery with radiotherapy, combination chemotherapy or both [1–4]. Risks associated with intensive treatments, including the possible occurrence of second malignancies, have led several investigators to evaluate less aggressive therapy. Pretreatment staging laparotomies are used to detect occult disease, especially in the spleen [5–7]. More recently, post-chemotherapy surgical restaging has been introduced to identify minimal residual disease and define further therapeutic strategies [8, 9].
KeywordsMinimal Residual Disease Complete Remission Rate Clinical Complete Remission Surgical Response Extended Field Irradiation
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