Some Aspects of Mutagenicity Testing of the Particulate Phase and the Gas Phase of Diluted and Undiluted Automobile Exhaust
- 80 Downloads
Mutagenicity testing of complex chemical mixtures always involves difficulties not encountered when testing individual chemicals. This is especially evident when testing automobile exhausts for mutagenicity in vitro, since many factors may affect the results. Some of these factors will be discussed.
KeywordsMutagenic Effect Cold Start Driving Cycle Automobile Exhaust Diesel Vehicle
Unable to display preview. Download preview PDF.
- Ames, B.N., J. McCann, and E. Yamasaki. 1975. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutation Res. 31:347–364.Google Scholar
- Egebäck, K.E., ed. (in press). Chemical and biological characterization of vehicle exhaust emissions when using different fuel/engine combinations. Report to the Swedish Government Committee on Automotive Air Pollution. The National Swedish Environment Protection Board, Motor Vehicle Section.Google Scholar
- Gibson, T.L., A.I. Ricci, and R.L. Williams. 1981. Measurement of polynuclear aromatic hydrocarbons, their derivatives, and their reactivity in diesel automobile exhaust. In: Chemical Analysis and Biological Fate: Polynuclear Aromatic Hydrocarbons. M. Cooke and A.J. Dennis, eds. Battelle: Columbus, pp. 707–717.Google Scholar
- Pederson, T.C. and J.-S. Siak. 1981b. Dinitropyrenes: their probable presence in diesel particle extracts and consequent effect on mutagenic activations by NADPH-dependent S9 enzymes. Presented at the U.S. Environmental Protection Agency Diesel Emissions Symposium, Raleigh, NC.Google Scholar
- Rannug, U. 1982. Data from short-term tests on motor vehicle exhausts. Presented at the Karolinska Institute Symposium on Biological Tests in the Evaluation of Mutagenicity and Carcinogenicity of Air Pollutants, Stockholm, Sweden.Google Scholar
- Salmeen, I., A.M. Durisin, T.J. Prater, T. Riley, and D. Schuetzle. 1981. Contribution of 1-nitropyrene to direct acting Ames assay mutagenicities of diesel particulate extracts. Presented at the U.S. Environmental Protection Agency Diesel Emissions Symposium, Raleigh, NC.Google Scholar
- Stenberg, U., R. Westerholm, T. Alsberg, U. Rannug, and A. Sundvall. 1981a. Enrichment of PAH and PAH derivatives from automobile exhausts, by means of a cryo-gradient sampling system. Presented at the Sixth International Symposium on Polynuclear Aromatic Hydrocarbons, Columbus, OH.Google Scholar
- Stenberg, U., T. Alsberg, and R. Westerholm. 1981b. The applicability of a cryo-gradient technique for the enrichment of PAH from automobile exhaust, demonstration of methodology and evaluation experiments. Presented at the Karolinska Institute Symposium on Biological Tests in the Evaluation of Mutagenicity and Carcinogenicity of Air Pollutants, Stockholm, Sweden.Google Scholar
- Stump, F., R. Bradow, W. Ray, D. Dropkin, R. Zweidinger, J. Sigsky, and R. Snow. 1981. Trapping gaseous hydrocarbons for mutagenic testing. Presented at the U.S. Environmental Protection Agency Diesel Emissions Symposium, Raleigh, NC.Google Scholar