Nongonococcal Urethritis

  • Yehudi M. Felman
  • King K. Holmes


The etiology of urethritis in homosexual men differs from its etiology in heterosexual men in at least two major ways. First, it is quite clear that the relative frequencies of gonorrhea and nongonococcal urethritis are different for the two groups. Homosexual men have predominantly gonococcal urethritis (GU), and, in many areas of the United States, heterosexual men have predominantly nongonococcal urethritis (NGU). The relative frequency of GU/NGU is also related to race, but this may be for different reasons. In sexually transmitted disease (STD) clinics, heterosexual black men with urethritis more often have GU than NGU, while the reverse is true for heterosexual white men. This has suggested to some that blacks may be more susceptible to gonorrhea and whites more susceptible to NGU. However, in a United States Navy cohort study1 done recently on an aircraft carrier, it was found that black men had a higher risk of GU than white men, but they also had a higher risk of NGU. GU is more symptomatic than NGU; it is therefore possible that racial or cultural differences in the response to symptoms account for some of the differences in apparent frequency of GU and NGU in various population groups in the STD clinic setting.


Chlamydia Trachomatis Neisseria Gonorrhoeae Sexually Transmitted Disease Ureaplasma Urealyticum Gonococcal Urethritis 
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  1. 1.
    Harrison WO, Hooper RR, Wiesner PF, et al: A trial of minocycline given after exposure to prevent gonoithea. N Engl J Med 300: 1074–1078, 1979.PubMedCrossRefGoogle Scholar
  2. 2.
    Evaluations and Statistical Services Section, Venereal Disease Control Division, Centers for Disease Control, Atlanta.Google Scholar
  3. 3.
    Willcox RR: How suitable are available pharmaceuticals for the treatment of sexually transmitted diseases? 1. Conditions presenting as genital discharges. Br J Vener Dis 53: 314–323, 1977.PubMedGoogle Scholar
  4. 4.
    Wiesner PJ: Selected aspects of the epidemiology of nongonococcal urethritis, in Hobson D, Holmes KK (eds): Nongonococcal Urethritis and Related Infections. Washington, DC, American Society for Microbiology, 1977, pp 9–14.Google Scholar
  5. 5.
    McCormack WM: Etiology of nongonococcal urethritis-One piece in the puzzle. N Engl J Med 292: 1238–1239, 1977.CrossRefGoogle Scholar
  6. 6.
    Goldneier D, Darougar S: Isolation of Chlamydia trachomatis from throat and rectum of homosexual men. Br J Vener Dis 53: 184–185, 1977.Google Scholar
  7. 7.
    Simmons P, Senior Registrar, St. Bartholomew’s Hospital, London, England, personal communication.Google Scholar
  8. 8.
    Bowie WR, Wang SP, Alexander ER, et al: Etiology of nongonococcal urethritis. Evidence for Chlamydia trachomatis and Ureaplasma urealyticum. J Clin Invest 59: 735–742, 1977.PubMedCrossRefGoogle Scholar
  9. 9.
    Holmes KK: Nongonococcal urethritis: General considerations and specific considerations for homosexual men. J Homosexuality 5: 295–298, 1980.CrossRefGoogle Scholar
  10. 10.
    Bowie WR, Wang SP, Alexander ER: Etiologies of postgonococcal urethritis in homosexual and heterosexual men: Role of Chlamydia trachomatis and Ureaplasma urealyticum. Sex Transm Dis 5: 151–154, 1978.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Yehudi M. Felman
    • 1
    • 2
    • 3
  • King K. Holmes
    • 4
    • 5
  1. 1.Department of DermatologyState University of New York, Downstate Medical SchoolBrooklynUSA
  2. 2.Department of Preventive MedicineState University of New York, Downstate Medical SchoolBrooklynUSA
  3. 3.Department of Community HealthState University of New York, Downstate Medical SchoolBrooklynUSA
  4. 4.Division of Infectious DiseasesSeattle Public Health HospitalSeattleUSA
  5. 5.Department of MedicineUniversity of Washington at SeattleSeattleUSA

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