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Effective Salvage Therapy for Refractory Disseminated Breast Cancer with 5-Fluorouracil and High-Dose Continuous Infusion Folinic Acid

  • James H. Doroshow
  • Lucille Leong
  • Kim Margolin
  • Bridget Flanagan
  • David Goldberg
  • Marcelle Bertrand
  • Steven Akman
  • Brian Carr
  • O. Odujinrin
  • Terri Litchfield
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 244)

Abstract

Treatment options are limited for patients with disseminated carcinoma of the breast whose disease has progressed after therapy with standard chemotherapeutic programs (1). In fact, the usefulness of testing investigational agents in those breast cancer patients who have been heavily pretreated, (two or more prior regimens), has been questioned recently (2). Thus, the discovery of effective therapy for this patient population is of considerable interest.

Keywords

Breast Cancer Metastatic Breast Cancer Advanced Breast Cancer Objective Response Rate Folinic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • James H. Doroshow
    • 1
  • Lucille Leong
    • 1
  • Kim Margolin
    • 1
  • Bridget Flanagan
    • 1
  • David Goldberg
    • 1
  • Marcelle Bertrand
    • 1
  • Steven Akman
    • 1
  • Brian Carr
    • 1
  • O. Odujinrin
    • 1
  • Terri Litchfield
    • 1
  1. 1.Departments of Medical OncologyTherapeutics Research and Biostatistics City of Hope Cancer Research CenterDuarteUSA

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