The Effect of Lithium Carbonate Administration in Patients with Advanced Small Cell Bronchogenic Carcinoma Receiving Combination Chemotherapy and Radiotherapy

  • Gary H. Lyman
  • Charles C. Williams
  • William R. Dinwoodie
  • Dennis Preston
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 127)


Undifferentiated small cell bronchogenic carcinoma accounts for 15–20% of all forms of lung cancer. It is characterized by sudden onset of symptoms, evidence of widespread disease at presentation and a rapidly progressive clinical course (Broder et al., 1977). The short tumor doubling time and the large growth fraction found in this histologic type may account for both its characteristic clinical features and its sensitivity to cytotoxic treatments (Muggia et al., 1974).


Small Cell Lung Cancer Partial Remission Objective Response Rate Small Cell Carcinoma Extensive Disease 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Gary H. Lyman
    • 1
  • Charles C. Williams
    • 1
  • William R. Dinwoodie
    • 1
  • Dennis Preston
    • 1
  1. 1.Department of Internal MedicineUniversity of South Florida College of Medicine and the Tampa Veterans Administration HospitalTampaUSA

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