Biology of the Lithium Ion

  • Ghanshyam N. Pandey
  • John M. Davis
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 127)


Lithium is used effectively in the treatment of acute mania. During maintenance therapy, it reduces the frequency of manic-depressive episodes. Lithium has also recently been used in the treatment of several other pathologic conditions such as schizophrenia, alcoholism, aggression, tardive dyskinesia, and Huntington’s chorea; however, its therapeutic efficacy in such conditions may be controversial. Although lithium is one of the most effective drugs used in the treatment of manic-depressive illness, its mode of action remains unclear.


Adenylate Cyclase Bipolar Patient Lithium Transport Platelet Adenylate Cyclase Platelet Adenylate Cyclase Activity 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Ghanshyam N. Pandey
    • 1
  • John M. Davis
    • 2
  1. 1.Research DepartmentIllinois State Psychiatric InstituteChicagoUSA
  2. 2.Department of Psychiatry Pritzker School of MedicineUniversity of ChicagoChicagoUSA

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