Cholera pp 189-197 | Cite as

Colonization and Pathology

  • R. Bradley Sack
Part of the Current Topics in Infectious Disease book series (CTID)


The pathogenesis of cholera has been well characterized during the past 25 years in several animal models and cholera patients. From these studies has come an understanding of this disease which is perhaps the most complete of any infectious disease. Clearly, there are still gaps in our knowledge about many of the details of the host-parasite relationship, but the major events (inoculum size, colonization, and enterotoxin production and its physiologic effects) are known, and from this knowledge specific interventions have been devised to interfere with the establishment of the infection, aid in treating it, or hasten its termination.


Small Bowel Outer Membrane Protein Inoculum Size Cholera Vaccine Colonization Factor 
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© Springer Science+Business Media New York 1992

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  • R. Bradley Sack

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