Hairy cell leukemia (HCL) is a rare disease, involving approximately 600 new patients each year in the United States. The median age at the time of diagnosis is approximately 52 years, and about one-half of the cases occur between 40 and 60 years of age, but have occurred as young as 22 and as old as 86 years of age. Men are affected more often than women by a ratio of approximately 4 to 1. There is a familial inheritance pattern in approximately 1 % of the cases with clear parent and child diagnoses of HCL. Other suggested environmental associations such as radiation or benzene exposures have been repudiated.
KeywordsMinimal Residual Disease Hairy Cell Leukemia Hairy Cell Purine Analogue Benzene Exposure
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