• Soft tissue infections can be classified as either simple or necrotizing. • Necrotizing soft tissue infections (NSTI) generally involve the subcutaneous tissue, fascia, or deeper tissues. Therefore, an NSTI may not be readily apparent on external inspection of the skin. • Patients with a history of blunt or penetrating trauma, diabetes mellitus, illicit parenteral drug use, burns, bites, stings, recent surgery, immunologic deficiency, or soft tissue contamination are at risk for NSTI. • Initial management of NSTI includes administration of antibiotics, hemodynamic monitoring and physiologic stabilization, treatment of electrolyte/acid-base imbalances, and correction of coagulopathy. • Treatment consists of urgent surgical exploration with drainage and debridement of nonviable or infected tissue. Wounds require frequent inspection until one is assured that tissues remain viable and infection is no longer spreading.
KeywordsSoft Tissue Infection Necrotizing Fasciitis Hyperbaric Oxygen Therapy Fecal Diversion Clostridial Myonecrosis
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