Brain and Heart Dynamics

  • Stefano Govoni
  • Pierluigi Politi
  • Emilio Vanoli
Reference work

Table of contents

  1. Front Matter
    Pages i-xxxv
  2. Functional Anatomy and Molecular Basis of the Cardiac-Brain Axis

    1. Front Matter
      Pages 1-1
    2. Veronica Dusi, Jeffrey L. Ardell
      Pages 3-24
    3. Alessia Pascale, Stefano Govoni
      Pages 25-41
    4. Edoardo Gronda, Emilio Vanoli
      Pages 43-53
    5. Ilaria Liguori, Francesco Curcio, Pasquale Abete, Gianluca Testa
      Pages 79-93
  3. Inflammatory Processes Perturbing Brain-Heart Dialogue

    1. Front Matter
      Pages 95-95
    2. Laura Calvillo, Gianfranco Parati
      Pages 97-115
    3. Pietro Cipresso, Javier Fernández Alvarez, Giuseppe Riva, Laura Calvillo
      Pages 147-163
  4. Emotional Processes and How They May Influence Cardiovascular Activity, Disease Onset, Outcomes, and Quality of Life

    1. Front Matter
      Pages 165-165
    2. Fredric Shaffer, Donald Moss
      Pages 167-179
    3. Alessandro Rodolico, Ludovico Mineo
      Pages 181-196
    4. Enrico Baldi, Simone Savastano
      Pages 197-211
    5. Umberto Provenzani
      Pages 213-227
    6. Stefania Balzarotti, Barbara Colombo, Amanda Christensen
      Pages 229-239
  5. Bidirectional Influences of Common Psychiatric Conditions and Cardiovascular Activity

    1. Front Matter
      Pages 241-241
    2. Laura Fusar-Poli, Davide Arillotta
      Pages 243-260
    3. Phillip J. Tully, Suzanne Cosh, Susanne Pedersen
      Pages 261-279
    4. Isabella Masci, Sergio Merlino, Grazia Rutigliano
      Pages 281-295
    5. Camilla Gesi, Barbara Carpita, Filippo M. Barberi, Annalisa Cordone, Liliana Dell’Osso
      Pages 297-313
    6. Annalisa Boldrini
      Pages 315-333
    7. Federica Calorio, Cristina Grazia Catania, Matteo Rocchetti
      Pages 335-353
    8. Claudia Carmassi, Annalisa Cordone, Virginia Pedrinelli, Liliana Dell’Osso
      Pages 355-376
    9. Simone Savastano, Enrico Baldi, Natascia Brondino
      Pages 377-385
    10. Benedetta Vanini, Claudio Placenti, Andrea M. D’Armini
      Pages 387-398
    11. Pierluigi Politi, Valentina Martinelli
      Pages 399-409
    12. Marinella Sommaruga, Antonia Pierobon
      Pages 411-425
  6. Neurological Diseases and How They May Influence Cardiovascular Activity, Disease Onset, Outcomes, and Quality of Life

    1. Front Matter
      Pages 427-427
    2. Marco Vercesi
      Pages 429-444
    3. Giulia Perini, Matteo Cotta Ramusino, Sara Bernini, Alfredo Costa
      Pages 445-463
    4. Giuseppe Micieli, Isabella Canavero
      Pages 465-479
    5. Anna Cavallini, Serena Magno, Alessandra Persico, Andrea Morotti
      Pages 481-496
    6. Francesca Pistoia, Simona Sacco, Marco Sarà, Antonio Carolei
      Pages 497-506
    7. Raffaele Manni, Gianpaolo Toscano, Michele Terzaghi
      Pages 507-515
    8. Cristina Tassorelli, Roberto De Icco, Daniele Martinelli, Michele Viana
      Pages 517-527
    9. Camilla Rocchi, Giorgia Mataluni, Doriana Landi
      Pages 529-540
  7. Sleep and Heart

    1. Front Matter
      Pages 559-559
    2. Edgar Toschi-Dias, Eleonora Tobaldini, Nicola Montano, Luigi Ferini-Strambi
      Pages 561-573
    3. Michele Terzaghi, Gianpaolo Toscano, Raffaele Manni
      Pages 575-584
    4. Alessandro Silvani
      Pages 585-602
  8. Pain and Heart

    1. Front Matter
      Pages 603-603
    2. Elena G. Bignami, Alberto Castella
      Pages 605-614
    3. Philippe Mavrocordatos, Gustavo Rodrigues Costa Lages, Lucian Mihai Macrea
      Pages 615-631
    4. Dario Bugada, Valentina Bellini, Elena G. Bignami, Luca F. Lorini
      Pages 633-647
    5. Giustino Varrassi, Joseph Pergolizzi, John F. Peppin, Antonella Paladini
      Pages 649-670
    6. Giovanna Goldaniga, Massimo Allegri
      Pages 671-679

About this book


This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest.
Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling.

Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the core topic: from social and philosophical to gender-related aspects.
It is designed for a broad readership and  includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease. 


Brain-heart axis Brain-heart communication Brain-Heart Efferent Pathways Cardiac Innervation Cardiac Homeostasis Heart Activity and Cognition Emotional Processing and Heart Activity Biofeedback Depression and Cardiovascular Disease Bipolar Disorder and cardiovascular risk Cardiovascular Manifestations of Anxiety and Panic Cardiac Transplantation and Psychopathology Heart Diseases and Dementias Heart and Stroke Heart and Parkinson disease Neurocardiac Syndromes Psychiatric Effects of Cardiovascular Drugs Neurological Effects of Cardiovascular Drugs Cardiovascular Effects of Psychiatric Drugs Interdisciplinary care

Editors and affiliations

  • Stefano Govoni
    • 1
  • Pierluigi Politi
    • 2
  • Emilio Vanoli
    • 3
  1. 1.Department of Drug Sciences, Section of PharmacologyUniversity of PaviaPaviaItaly
  2. 2.Department of Brain and Behavioral SciencesUniversity of PaviaPaviaItaly
  3. 3.Department of Molecular MedicineUniversity of PaviaPaviaItaly

Bibliographic information