• Martin GlasEmail author
  • Björn Scheffler
  • Sied Kebir
Living reference work entry

Later version available View entry history

Part of the Springer Reference Medizin book series (SRM)


Gliome repräsentieren etwas mehr als ein Drittel aller primären Hirntumoren. Dazu gehören Astrozytome, Oligodendrogliome und die Ependymome. Glioblastome als bösartigste Variante astrozytärer Gliome sind am häufigsten. Gliome werden nach ihrem biologischen Verhalten und nach ihrer Histopathologie entsprechend der WHO-Klassifikation in die Malignitätsgrade I–IV eingeteilt. Diese Gradierung besitzt große prognostische Bedeutung. Die molekularen Parameter IDH1/2-Mutationsstatus und 1p/19q-Kodeletion helfen bei astrozytären und oligodendroglialen Tumoren bei der Planung der Chemotherapie.


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Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2019

Authors and Affiliations

  1. 1.Abteilung Klinische Neuroonkologie, Klinik und Poliklinik für NeurologieUniversitätsklinikum EssenEssenDeutschland
  2. 2.DKFZ Abteilung Translationale Neuroonkologie am Westdeutschen TumorzentrumDKTK Partnerstandort Universitätsklinikum EssenEssenDeutschland

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